Metabolic drug name patterns:

• gliFLOZIN - SGLT2 inhibitor - blocks reabsorption of glucose in the proximal convoluted tubule (glucosuria -> UTIs, vulvovaginal candidiasis, dehydration [glucose is osmotically active], orthostatic hypotension, hyperkalemia)
• gliNIDE - Meglitinide - insulin secretagogues (similar to 1st and 2nd generation sulfonylureas) that close K+ channels in pancreatic B cell membranes leading to depolarization and insulin release via increased Ca++ influx
• gliPTIN - DPP-4 inhibitor - inhibits the deactivation of GLP-1 which decreases glucagon release and delays gastric emptying (similar to GLP-1 analogs such as exenatide)
• gliTAZONE (or thiazolidinediones) - PPAR-gamma activator (increases insulin sensitivity and levels of adiponectin)
• gluTIDE - GLP-1 analog

PPAR-alpha activator - Fibrates (gemfibrozil, bezafibrate, and fenofibrate) [cause major triglyceride decrease, and induces HDL synthesis]