• Older patient with dementia, decreased DTRs, non-pitting edema of the lower extremities and slow movements, most consistent with hypothyroidism
• Huntington disease –> Dementia, depression, chorea
• Multi-infarct (vascular) dementia –> Step-wise dementia with focal neurologic defects (weakness, sensation, etc.)
• Pernicious anemia –> Atrophic gastritis + B12 deficiency (lower extremity weakness, paresthesias, sensory disturbances, etc.)
• Syphilis –> Lymphadenopathy, diffuse rash involving the palms and soles

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