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increase in cAMP (Gs) - beta2 - vasodilation

decrease in cAMP (Gi) - alpha2 - vasoconstriction

increase in IP3 DAG (Gq) - alpha1 - vasoconstriction

increase in cGMP - M3 - NO induced vasodilation

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cytotoxict  Alpha 2 agonists do not cause vasoconstriction b/c they lead to negative feedback of norepi and thus decrease sympathetic response +1
payingforthisisdumb  FA20 p317 α2-agonists increase NO/cGMP and vasodilate +
sarahs  why is decreasing cAMP wrong? +1
hiroshimi  @sarahs: you want to increase cAMP because it would lead to vasodilation and help to decrease his blood pressure. Decreasing cAMP would make his BP worse. +
fatboyslim  alpha2 stimulation causes vasodilation because it is sympatholytic. +


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