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NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
35-year-old woman has an abnormal Pap smear. ...
Neoplastic cells in the sub-basement membrane connective tissue ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +4  upvote downvote
submitted by โˆ—cassdawg(1780)
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This is basically a question of terminology. (FA2020 p219)

Invasive means it has penetrated the basement membrane but "microinvasive" would assume it has not invaded surrounding tissues as it has not metastasized.

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dhkahat  am i crazy here? This questions seems odd to me. Because full thickness of the epithelium had to have been covered by neoplastic cells first right? idk maybe i got confused by the wording what "lead to this diagnosis" +1
j44n  what they're talking about with that one is a carcinoma insitu-> IE its neoplastic but it has yet to invade +1
ali_hassan  so basically the full thickness of epithelium has been occupied and it's gone slightly beyond into the-basement membrane tissue, but not the actual membrane tissue (hence "micro"invasion) +2



 +1  upvote downvote
submitted by solangelroma(2)
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microinvasion as a lesion that invaded below the basement membrane to a depth of 3 mm or less, with no evidence of invasion of the lymphovascular space.

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