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Retired NBME 29 Answers

nbme29/Block 1/Question#18 (reveal difficulty score)
Patients with prolonged starvation or ...
Increased availability of acetyl CoA ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem

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submitted by โˆ—namesthegame22(13)
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Both starvation and untreated type 1 diabetes mellitus result in an increased rate of fatty acid oxidation, which generates acetyl CoA to be used in the citric acid cycle and NADH.

Concomitant ketogenesis results in the formation of ketone bodies that can be detected in serum and urine.

Decreased activity of the Pentose Phosphate pathway would not lead to the generation of ketones.

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