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step2ck_form7/Block 2/Question#32 (4.1 difficulty score)
A 57-year-old woman with factor XI and IgA ...
Anaphylactic transfusion reaction๐Ÿ”,๐Ÿ“บ

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submitted by step_prep5(196),
  • Key idea: IgA deficiency classically leads to Anaphylaxis to IgA-containing blood products + Atopy + Autoimmune disease + GI/sinopulmonary infections (IgA involved in mucosal immunity)
  • Anaphylactic transfusion reaction: Respiratory distress/wheezing, angioedema, hypotension, hives/urticaria
  • Urticarial transfusion reaction: Angioedema, wheezing

sassy_vulpix  Patient is a known case of IgA deficiency and we still gave them blood products with IgA? +3  

submitted by embeemee(1),

what is "allergic nonhemolytic transfusion reaction"? i thought it was the febrile one, but febrile is listed separately