72 year old patient with lung cancer presents with non-fatigable weakness affecting the eyes and proximal muscles (hip extensors, eyes), autonomic symptoms (dry mouth, constipation) and loss of deep tendon reflexes, most consistent with Lambert-Eaton syndrome (which can be diagnosed with repetitive nerve stimulation)
Myasthenia gravis: Associated with thymoma, oculobulbar weakness that worsens with repeated use
Lambert-eaton syndrome: Associated with small cell lung cancer, proximal muscle weakness that improves with repetitive use AND autonomic dysfunction and decreased/absent deep tendon reflexes
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