NBME Step 2 CK Form 8 Complete atrioventricular block (NBME Answers)

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NBME Step 2 CK Form 8 Answers

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A 30-year-old primigravid woman with systemic ...
Complete atrioventricular block 🔍 / 📺 / 🌳 / 📖
tags: cardio rheum inc

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submitted by ∗step_prep(148)

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Signs/symptoms of neonatal lupus include congenital heart block, rash and thrombocytopenia
Key idea: Only occurs if lupus patient has antibodies against SSA and SSB

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submitted by ∗link981(208)

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SLE like other autoimmune diseases, may improve or worsen, or can present for the first time during pregnancy. Obstretic complications related to SLE: -Maternal (preeclampsia), - -Fetal (neonatal lupus, intrauterine fetal demise)-

-Neonatal lupus occurs due to passive placental transfer of maternal anti-SSA (Ro) and anti-SSB (La) antibodies (30% prevalent in SLE.-

-Fetal findings: -Cardiac (fetal AV block) that occurs due to maternal autoantibodies binding to fetal cardiac cells. Causes irreversible injury to AV nose. The ventricular heart rate will determine the baseline fetal heart rate and will present with fetal bradycardia (less than 110 beats per minute). - -If the heart block is prolonged, hydrops fetalis can occur.

(https://www.jpedhc.org/article/S0891-5245(13)00232-0/fulltext) Uworld Question ID (12531)

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