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Retired NBME Step 2 CK Free 120 Answers

step2ck_free120/Block 1/Question#33 (reveal difficulty score)
A 67-year-old woman comes to the physician ...
Bone marrow aspiration ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: hemeonc

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submitted by โˆ—bwdc(697)
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Thrombocytopenia without antiplatelet antibodies or splenomegaly implies a platelet production problem (e.g. myelofibrosis). History of radiation therapy is a risk factor. The only way to know whatโ€™s happening at the factory is a bone marrow biopsy.

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dmk21  i don't think that's 100% right myelofibrosis will have splenomegaly +2
tinylilron  I wonder if this could be Idiopathic Thrombocytopenic Purpura due to the only abnormality being the low platelet count. First Aid says that "Bone marrow biopsy would show increased megakaryocytes but is done only in atypical cases or patients > 60 years of age." +



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