@docinthehouse18 yes colon cancer spreads to distant organs via lymphatics e.g. to the lungs but the reason why the most common location of colon cancer metastasis is the liver is because of the unique anatomic situation with regards to portal venous system. so colon cancer spreads to the liver hematogenously via portal venous system but otherwise spreads to distant sites via lymphatics. the question asks the route of metastasis to the liver and tumor seeding of the abdominal cavity from the colonic tumor will not cause mets in liver. 4 carcinomas that spreads hematogenously only and only spreads via blood.