need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

NBME 15 Answers

nbme15/Block 3/Question#41 (reveal difficulty score)
A 56-year-old woman is brought to the ...
1000 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +17  upvote downvote
submitted by โˆ—cassdawg(1780)
get full access to all contentpick a username

Here, we want to know loading dose which is equal to the volume of distribution x target concentration in plasma.

So our loading dose = 1.81L/kg x 10mg = 18.1mg/kg

She is a 55kg person so 18.1mg/kg x 55kg = 995.5 mg which approximates to 1000mg total loading dose.

Important Pharm Equations to Remember

get full access to all contentpick a username
cassdawg  10mg/L * sorry +1
cheesetouch  fa2018 p229 +2



 +0  upvote downvote
submitted by โˆ—pakimd(31)
get full access to all contentpick a username

loading dose= [target plasma conc. (at steady state) x vol of distribution / bioavailability] x weight

bioavailability is 100% if IV dose. so bioavailability is 1 (100/100= 1 which is 100%)

now loading dose is:

10 mg/L x 1.81 L/kg X 55 kg

(cut all the common units in numerator and denominator)

you get-- 10 mg x 1.81 x 55 = 995.5 mg ~ 1000 mg total loading dose

get full access to all contentpick a username



Must-See Comments from nbme15

cassdawg on Deoxyhemoglobin is a better buffer of ...
andro on T-lymphocyte thymocytes localized to the ...
cassdawg on Burning
cassdawg on 1000
cassdawg on Left ventricular pressure increased, right ...
cassdawg on Pancreatic enzymes
cassdawg on Decreased smoking
cassdawg on Low blood solubility
cassdawg on Glutamine
cassdawg on Prolonged fecal excretion of the organism
cassdawg on The neural plate is present, but the neural ...
cassdawg on Immunohistochemistry
cassdawg on epp Amplitude: 1; mepp Amplitude: 1; ...
cassdawg on Action of pancreatic enzymes on adipose

search for anything NEW!