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NBME 15 Answers

Block/Question (3.9 difficulty score)
An 18-year-old man is brought to the physician by his father ...
Inquiry about a history of anabolic steroid use

Block/Question (1.5 difficulty score)
A 45-year-old man has a 2-day history of severe abdominal pain
Action of pancreatic enzymes on adipose

Block/Question (6.0 difficulty score)
A 72-year-old woman is admitted to the hospital because of an ...
Left coronary, circumflex, posterior interventricular (posterior descending)

Block/Question (1.1 difficulty score)
A 32-year-old woman comes to the physician because of a 6-month
Collecting duct

Block/Question (1.0 difficulty score)
A 50-year-old woman comes to the physician because of progressive
Endothelin

Block/Question (2.3 difficulty score)
Following a stroke, a 68-year-old man has a language problem. His
H (Wernicke's area)

Block/Question (4.4 difficulty score)
A previous healthy 26-year-old woman comes to the physician ...
Area labeled by letter 'E'

Block/Question (1.8 difficulty score)
A 55-year-old man comes to the physician because of a 2-month hist
Motor fibers from the vagus nerve

Block/Question (3.9 difficulty score)
A 56-year-old woman is brought to the emergency department by ...
Lipopolysaccharide

Block/Question (0.9 difficulty score)
A 23-year-old primigravid woman develops fever and chills 2 days
Listeria monocytogenes

Block/Question (3.3 difficulty score)
A 30-year-old man is brought to the physician by his wife ...
Porphobilinogen deaminase

Block/Question (0.9 difficulty score)
During an experiment of muscle contraction, intracellular calcium
Myosin bonding sites on actin remain covered by troponin C

Block/Question (5.2 difficulty score)
A 37-year-old woman is brought to the emergency department ...
Cardiogenic

Block/Question (5.7 difficulty score)
A 65-year-old man with hypertension volunteers to participate ...
Acid-base: Metabolic alkalosis; Volume contraction: yes

Block/Question (4.4 difficulty score)
A 65-year-old woman comes to the physician for a follow-up ...
Osteoblast activity: decreased; Osteoclast activity: increased; RANKL: increased

Block/Question (4.2 difficulty score)
A 22-year-old woman is found to be HIV positive after sexual ...
Protein processing

Block/Question (3.2 difficulty score)
A 70-year-old woman is found dead in her bed in a skilled ...
Hypertrophy

Block/Question (1.4 difficulty score)
A 69-year-old man with benign prostatic hyperplasia develops
Bethanechol

Block/Question (1.1 difficulty score)
An 18-year-old man comes to the physician because of 1-year
Prolactin

Block/Question (1.4 difficulty score)
A 35-year-old metal worker collapses after exposure to an unknown
Amyl nitrite

Block/Question (4.8 difficulty score)
An 18-month-old boy with severe combined immunodeficiency ...
Irradiated packed red blood cells

Block/Question (2.8 difficulty score)
A 31-year-old woman is treated for Plasmodium vivax malaria ...
Primaquine kills hypnozoites

Block/Question (1.2 difficulty score)
A 25-year-old primigravid woman at 12 weeks' gestation comes to th
Partial hyatidiform mole

Block/Question (2.6 difficulty score)
A 72-year-old man comes to the physician because of a 3-month hist
Protrusion of the fundus into the chest above the level of T10

Block/Question (4.6 difficulty score)
A 50-year-old man comes to the physician for a routine health ...
Medullary

Block/Question (3.8 difficulty score)
A couple has two children with osteogenesis imperfecta type ...
Germline mosaicism

Block/Question (1.0 difficulty score)
A 71-year-old woman is brought to the emergency department 1 hour
Temporal arteritis

Block/Question (1.2 difficulty score)
A 32-year-old man is brought to the emergency department in a coma
pH 7.28, PO2(mmHg) 50, PCO2(mmHg) 60, HCO3-(mEq/L) 27

Block/Question (5.2 difficulty score)
A 25-year-old woman with a history of rheumatic fever and ...
Streptococcus mitis

Block/Question (0.9 difficulty score)
An 8-year-old boy with moderate mental retardation is brought
Prader-Willi syndrome

Block/Question (3.1 difficulty score)
A 42-year-old woman with multiple sclerosis is brought to the ...
Medial longitudinal fasciculus

Block/Question (5.4 difficulty score)
A 75-year-old woman is brought to the physician because of a ...
Releases NF-κB after undergoing phosphorylation

Block/Question (1.5 difficulty score)
A 54-year-old man comes to the physician because of increasing
Major depressive disorder

Block/Question (1.0 difficulty score)
A 3-year-old girl is brought to the physician because of fever and
Dynein

Block/Question (3.3 difficulty score)
A 2-month-old boy is brought to the physician because of ...
Peroxisomes

Block/Question (4.3 difficulty score)
A 1-year-old boy is brought to the physician by his parents ...
RNA splice error

Block/Question (1.3 difficulty score)
A food handler has a fresh furuncle on his face. He prepares
Vomiting

Block/Question (1.0 difficulty score)
A 45-year-old man with chronic renal failure is admitted
25-hydroxycholecalciferol

Block/Question (7.0 difficulty score)
A 43-year-old man with a 10-year history of alcoholism comes ...
Decreased glutathione

Block/Question (4.4 difficulty score)
A 36-year-old man who is heterozygous for an LDL-receptor ...
LDL receptor

Block/Question (7.5 difficulty score)
A 56-year-old woman comes to the physician because of a ...
Helicobacter pylori

Block/Question (4.4 difficulty score)
A 5-year-old boy is stung on his foot by a bee. Within 30 ...
Gap formation between endothelial cells

Block/Question (1.4 difficulty score)
A 50-year-old man is brought to the physician because of progressi
"D" label in the image

Block/Question (5.4 difficulty score)
A 45-year-old woman (III,7) comes to the physician for a ...
Incomplete penetrance

Block/Question (1.6 difficulty score)
A 67-year-old man comes to the physician because of a 2-month
Burning

Block/Question (0.9 difficulty score)
A 4-year-old boy has respiratory tract colonization with Pseudomon
Autosomal recessive

Block/Question (4.4 difficulty score)
A 23-year-old woman comes to the physician because of a ...
Glucokinase

Block/Question (4.2 difficulty score)
A newborn delivered at 28 weeks' gestation is in severe ...
Lung elastic recoil

Block/Question (0.2 difficulty score)
A 24-year-old woman is admitted to the hospital because of acute p
Ectopic pregnancy

Block/Question (1.2 difficulty score)
A 15-year-old is brought to the physician because of right wrist
Avascular necrosis of the proximal scaphoid bone

Block/Question (1.2 difficulty score)
A 34-year-old woman who is a scientist is brought to the
Potassium iodide

Block/Question (4.6 difficulty score)
An investigator is studying Helicobacter pylori strains ...
Slipped-strand mispairing

Block/Question (1.2 difficulty score)
A 24-year-old man develops recurrent vesicular lesions on his uppe
Sensory neurons

Block/Question (1.1 difficulty score)
A 45-year-old man with an ulcer in the anterior superior portion
Diaphragm

Block/Question (3.8 difficulty score)
A previously healthy 48-year-old man is brought to the ...
Degenerating epithelial cells and dirty brown granular casts

Block/Question (7.2 difficulty score)
A 2-year-old girl is brought to the emergency department 20 ...
Atropine

Block/Question (1.2 difficulty score)
A 43-year-old man comes to the physician because of progressive
Inherited protease deficiency

Block/Question (5.0 difficulty score)
A newborn undergoes surgical repair of esophageal atresia. ...
Endoderm

Block/Question (4.9 difficulty score)
A 4-year-old boy is brought to the physician by his father ...
Cytoskeleton

Block/Question (5.1 difficulty score)
A 4-day-old male newborn who was born at home is brought to ...
First

Block/Question (1.2 difficulty score)
A 17-year-old boy comes to the physician because of a 4-month hist
Tuberculosis abscess of the spine

Block/Question (2.6 difficulty score)
Influenza virus strains are characterized by differing sensitivity
HA

Block/Question (1.0 difficulty score)
A 21-year-old woman at 30 weeks' gestation is admitted to the hos
Cyclooxygenase

Block/Question (1.5 difficulty score)
A 1-month old male newborn is brought to the physician for a well-
Number of Melanocytes = Normal, Melanosomes = ↓

Block/Question (7.3 difficulty score)
A 2-month-old male infant is brought to the emergency ...
Glycine receptor

Block/Question (0.2 difficulty score)
a 4-year-old boy with asthma is brought to the emergency departmen
Binding to its cytoplasmic receptor, translocation to the nucleus, and activation of transcription of target genes

Block/Question (1.4 difficulty score)
A 32-year-old man has a 3-month history of episodic epigastric
Decreased smoking

Block/Question (4.5 difficulty score)
A 9-year-old boy has mild mental retardation and a 4-year ...
Tuberous sclerosis

oncology hodgkin lymphoma mutation
Block/Question (3.9 difficulty score)
A 30-year-old woman has had Hodgkin disease that was ...
Therapy for Hodgkin disease causes mutations in hematopoietic stem cells, and one mutant cell progresses to leukemia

Block/Question (4.0 difficulty score)
A previously healthy 18-year-old woman comes to the physician ...
β-Lactamase production

Block/Question (1.2 difficulty score)
A 19-year-old woman is brought to the physician by her parents
Olanzapine

Block/Question (1.2 difficulty score)
A previously healthy 25-year-old woman comes to the physician for
Germ cells

Block/Question (6.7 difficulty score)
A 43-year-old woman comes to the physician because of a ...
Complex partial

Block/Question (1.5 difficulty score)
A 50-year-old man underwent a bowel resection for colon cancer
Hematogenous spread of colonic tumor via the portal venous system

Block/Question (0.9 difficulty score)
A 13-year-old girl is brought to the physician by her mother
Transcription

Block/Question (4.4 difficulty score)
A study was begun in the 1950s to determine the causes of ...
Cohort study

Block/Question (1.0 difficulty score)
The lymphoproliferative properties of the gammaherpesviruses
Nasopharyngeal carcinoma

Block/Question (1.1 difficulty score)
The vaccine against diphtheria confers protective immunity
Purified inactivated toxin

Block/Question (1.8 difficulty score)
An investigator who wishes to test the hypothesis that a number
Immunohistochemistry

Block/Question (1.0 difficulty score)
A 19-year-old woman comes to the physician for a follow-up examina
Doxycycline

Block/Question (1.2 difficulty score)
A 43-year-old woman is admitted to the hospital 40 minutes
Hippocampus

Block/Question (2.9 difficulty score)
A previously healthy 26-year-old woman comes to the physician ...
External hemorrhoid

Block/Question (7.3 difficulty score)
A healthy 25-year-old man participates in a study of muscle ...
epp Amplitude: 1; mepp Amplitude: 1; Response to Ach: 1

Block/Question (1.1 difficulty score)
A 51-year-old woman undergoes dilation and curettage for dysfuncti
Succinylcholine

Block/Question (3.7 difficulty score)
A 25-year-old woman comes to the physician because of general ...
Thrombocytopenia

Block/Question (4.1 difficulty score)
A 28-year-old African American man comes to the physician ...
Ethnicity

Block/Question (1.1 difficulty score)
A previously healthy 27-year-old woman is brought to the emergency
Superantigen activation of T lymphocytes

Block/Question (2.9 difficulty score)
A 32-year-old man comes to the physician for his annual ...
Schizoid personality disorder

Block/Question (1.0 difficulty score)
A 28-year-old woman is brought to the hospital by her boyfriend be
Determine the C-peptide concentration in the latest blood specimen drawn

Block/Question (1.2 difficulty score)
A 3-year-old girl is brought to the physician because of a 1-month
Thyroid follicles

Block/Question (4.2 difficulty score)
A study is conducted to evaluate the effectiveness of cough ...
Lack of blinding between groups

Block/Question (0.9 difficulty score)
A 54-year-old woman comes to the physician because of a 2-week his
This patient's medication has an agonist effect on endometrial estrogen receptors

Block/Question (4.3 difficulty score)
A paper says, "We chose the sample size to have an 80% power ...
5%, Type I error

Block/Question (3.7 difficulty score)
A 45-year-old man comes to the physician for a follow-up ...
Venous return: decreased; Carotid sinus baroreceptor activity: decreased; Cerebral blood flow: decreased

Block/Question (1.0 difficulty score)
A 53-year-old man develops a fever and hypotension while being
Clostridium perfringens

Block/Question (1.5 difficulty score)
A 56-year-old woman is brought to the emergency department because
1000

Block/Question (5.2 difficulty score)
A 6-year-old boy with severe mental retardation and ...
0.2 to 0.5

Block/Question (5.4 difficulty score)
A 4-year-old boy with a karyotype of 47,XY+21 develops ...
Excess lymphoblasts

Block/Question (5.1 difficulty score)
A 59-year-old man comes to the physician because of a 10-day ...
Imatinib

Block/Question (5.5 difficulty score)
A 35-year-old woman, gravida 1, para 1, comes to the ...
Nicotinic acetylcholine receptor

Block/Question (2.6 difficulty score)
A 51-year-old man with a 5-year history of Wegener ...
Hematuria

Block/Question (1.0 difficulty score)
A 38-year-old man is admitted to the hospital after sustaining
Vitamin K deficiency caused by depletion of the normal gut flora

Block/Question (5.1 difficulty score)
A 2-month-old girl is brought to the physician for a ...
Congenital neutropenia

Block/Question (4.9 difficulty score)
A 27-year-old man comes to the physician because of a 3-hour ...
Prolonged fecal excretion of the organism

Block/Question (1.4 difficulty score)
A 72-year-old man with poorly controlled hypertension is brought t
Decreased femoral pulses

Block/Question (1.5 difficulty score)
A 70-year-old man has a 4-month history of weight loss, abdominal
Pancreatic enzymes

Block/Question (4.2 difficulty score)
A 48-year-old woman comes to the emergency department because ...
Increased cardiac parasympathetic activity

Block/Question (3.6 difficulty score)
A 65-year-old man with a history of ischemic heart disease ...
33%

Block/Question (0.6 difficulty score)
A 14-year-old boy has fatigue, intermittent right lower
Vitamin B12 (cobalmin)

pharyngeal_arch digeorge
Block/Question (3.8 difficulty score)
A male newborn is delivered at term with a right-sided aortic ...
Third and fourth branchial pouches

Block/Question (1.0 difficulty score)
A 10-year-old girl with sickle cell disease is brought to the
Salmonella

Block/Question (1.1 difficulty score)
A study is conducted of patients with restrictive airway disease
Increased body fat is associated with lower lung capacity

Block/Question (1.6 difficulty score)
An investigator conducts a study of the molecular basis of von
Proteasome

Block/Question (7.8 difficulty score)
A 3-year-old girl is brought to the physician because of a ...
Abnormal targeting of these enzymes to lysosomes

Block/Question (1.4 difficulty score)
A male newborn has multiple congenital anomalies resulting from
Absence of adrenal medulla

Block/Question (1.4 difficulty score)
A previously healthy 35-year-old woman develops hypoxemia 35 min
PO2 50, PCO2 80, (A-a)O2 10

Block/Question (1.3 difficulty score)
An 82-year-old woman with alcohol dependence is admitted to the
Inadequate hydroxylation of collagen polypeptides

reproductive
Block/Question (0.3 difficulty score)
A 26 year old woman comes to the physician because of vaginal irri
oral metronidazole

Block/Question (6.6 difficulty score)
A 13-year-old boy is scheduled to receive chemotherapy for a ...
T-lymphocyte thymocytes localized to the thymic cortex

Block/Question (2.4 difficulty score)
A 6-year-old girl is brought to the physician for a follow-up exam
Glutamine

Block/Question (1.3 difficulty score)
A 30-year-old woman comes to the physician because of a 6-month hi
Serotonin

Block/Question (6.5 difficulty score)
A 3-year-old girl is brought to the physician because of a ...
Interferon-gamma receptor

Block/Question (1.0 difficulty score)
A 69-year-old woman is brought to the physician by her son because
Normal pressure hydrocephalus

Block/Question (0.8 difficulty score)
A 55 year old woman with colon cancer and a healthy ..
Apoptosis

Block/Question (0.9 difficulty score)
A 62-year-old woman comes to the physician because of a 3-week
Multiple myeloma

Block/Question (1.0 difficulty score)
A 23-year-old woman is brought to the emergency department by her
Heroin

Block/Question (1.5 difficulty score)
A 2-month old male infant with a ventricular septal defect is brou
Left ventricular pressure increased, right ventricular pressure decreased, left atrial pressure decreased

Block/Question (5.6 difficulty score)
A 64-year-old man comes to the physician because of a 2-month ...
Increased fibrosis in the interstitium

Block/Question (3.3 difficulty score)
A 23-year-old woman comes to the physician because of a 3-day ...
Oculomotor nerve

Block/Question (4.9 difficulty score)
During a series of normal skeletal muscle twitches, the ATP ...
ATP is quickly regenerated from creatine phosphate

Block/Question (8.0 difficulty score)
Which of the following best explains why deoxygenated blood ...
Deoxyhemoglobin is a better buffer of hydrogen ions than oxyhemoglobin

Block/Question (9.9 difficulty score)
A 7-year-old boy is brought to the physician because of a ...
Virion release

Block/Question (8.6 difficulty score)
A healthy 3-year-old boy has a cleft lip and palate. He has ...
Multifactorial

Block/Question (1.6 difficulty score)
A 75-year-old woman comes to the physician because of 3-month hist
Lentigo maligna

Block/Question (5.1 difficulty score)
An investigator is designing a study to compare a new ...
Stratification

Block/Question (2.2 difficulty score)
A 50-year-old man comes to the physician because of a 2-week histo
Stenosis of the right coronary artery

aspirin
Block/Question (1.0 difficulty score)
An 18-year-old woman is brought to the emergency department 2 hour
Bleeding time

Block/Question (1.3 difficulty score)
A 60-year-old woman develops a secreting adenoma of the
Calcium concentration in feces

neuro
Block/Question (4.6 difficulty score)
A 52-year-old man is brought to the physician 3 days after ...
No constriction because the retinal ganglion cells in the left eye have been destroyed

Block/Question (9.2 difficulty score)
A 47-year-old man is admitted to the hospital for treatment ...
Increased pulmonary capillary pressure

Block/Question (1.5 difficulty score)
A 3-year-old boy with chronic otitis media is scheduled to undergo
Low blood solubility

Block/Question (3.0 difficulty score)
A 22-year-old man is brought to the emergency department 30 ...
Deep fibular (peroneal)

Block/Question (1.0 difficulty score)
A study is conducted to assess a new prenatal test for Down syndro
99%

Block/Question (4.8 difficulty score)
A 40-year-old woman with breast cancer is brought to the ...
Occipital lobe

Block/Question (4.3 difficulty score)
A 25-year-old woman comes to the physician because of ...
Nuclear/retinoid X binding to DNA

Block/Question (3.1 difficulty score)
A 25-year-old primigravid woman at 25 weeks' gestation comes ...
Prematurity

Block/Question (2.3 difficulty score)
A 22-year-old man comes to the physician because of an 8-year hist
Decreased conjugation of bilirubin

Block/Question (3.0 difficulty score)
A 50-year-old man comes to the emergency department because of a 2
Anemia

Block/Question (1.3 difficulty score)
A 60-year-old man is brought to the emergency department
Reversible, dose-dependent

Block/Question (2.0 difficulty score)
A 20-year-old woman comes to the physician because her menstrual p
The neural plate is present, but the neural tube is not yet complete

Block/Question (1.2 difficulty score)
A 42-year-old woman comes to the physician for an exam
Beta-thalassemia minor

Block/Question (0.9 difficulty score)
A 7-month-old girl is brought to the physician for a well-child ex
Coarctation of the aorta

Block/Question (1.3 difficulty score)
A 27-year-old woman comes to the physician because of 1-month
Dilated cardiomyopathy

Block/Question (2.0 difficulty score)
A 30-year-old nulligravid woman comes to the physician because
Estrogen in adipose tissue

Block/Question (3.6 difficulty score)
A 17-year-old boy with chronic renal insufficiency undergoes ...
Hydronephrosis

Block/Question (1.0 difficulty score)
A 66-year-old woman with ovarian cancer comes to the emergency dep
Increased tubular hydrostatic pressure

Block/Question (1.1 difficulty score)
A 22-year-old man comes to the emergency department 30 minutes
Median

Block/Question (3.5 difficulty score)
One-half hour after an uncomplicated vaginal delivery, a ...
Oxytocin

Block/Question (4.7 difficulty score)
A 24-year-old woman with Marfan syndrome comes to the ...
Hypervolemia

Block/Question (1.4 difficulty score)
A 23-year-old nulligravid woman comes to the physician because she
Blockage of both fallopian tubes

Block/Question (5.5 difficulty score)
A 75-year-old man with chronic obstructive pulmonary disease ...
C5a

Block/Question (1.2 difficulty score)
Vision screening is performed on 4000 people who are older than 65
Unable to calculate due to insufficient data

Block/Question (1.1 difficulty score)
A 48-year-old woman comes to the physician because of a 2-month
Autoantibody (IgM) reactive with IgG

Block/Question (6.1 difficulty score)
A 67-year-old man is brought to the physician because of a ...
Aneurysm of the posterior communicating artery

Block/Question (1.2 difficulty score)
A 32-year-old woman comes to the physician for a follow-up exam
Internal iliac

Block/Question (2.9 difficulty score)
A 45-year-old man comes to the physician for an initial ...
Mitral regurgitation

Block/Question (4.0 difficulty score)
A 72-year-old woman comes to the physician because of diffuse ...
Osteomalacia

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