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Retired NBME 15 Answers

nbme15/Block 1/Question#50 (reveal difficulty score)
A 32-year-old man is brought to the emergency ...
pH 7.28, PO2(mmHg) 50, PCO2(mmHg) 60, HCO3-(mEq/L) 27 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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This man has overdosed (potentially on opioids due to the severe respiratory depression), which is causing him to hypoventilate (less breaths/minute and shallow breaths).

Hypoventilation leads to:

  • Decreased O2 from decreased overall ventilation
  • Increased CO2 because you are not expelling as much CO2 in breaths. He is also retaining more residual air with shallow breaths so there is more CO2.
  • Acidosis from retained CO2
  • Slightly increased bicarb (from normal of 24mEq/L) but not fully compensated because this is primarily a respiratory alkalosis and compensation thus takes time
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aazib05  correction: uncompensated respiratory ACIDOSIS +



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submitted by โˆ—agraham416(5)
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How do we tell the difference between uncompensated respiratory acidosis and compensated?

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