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Retired NBME 15 Answers

nbme15/Block 1/Question#10 (reveal difficulty score)
Which of the following best explains why ...
Deoxyhemoglobin is a better buffer of hydrogen ions than oxyhemoglobin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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xDemobioleyhngo sha a igrehh aKp hant ahnoeylmxgbio nda hust lwil ccteap dhygeonr soni reom ladeyri. iTsh is rniatpomt ni eth tibylai to "arc"ry C2O sa het mina sahniecmm fo OC2 prosntart si lclytaua ennrosoivc fo 2OC ot -H3OC C2O( + H2O g&-;t 3O-HC + )H+, tshu dyoebhiamgnxelo scairre eth H+ lewih OC3-H si osrdpretnta ni teh plasma to eth gs.nlu nbrogibiealamomhCan is tuayclla yoln abotu %20 of the 2OC aprrnttso nad 2CO ddevslois as O2C si 01;% sntatprro as HOC-3 si durona 0%7 fo teh OC2 staorptnr.

Hree is noteahr aigme of teh ecosprs.

rnhoteA moatitprn cpteas of hte sespcor to keat neot of that ehty klei ot ask uotab is hte lcdoiehr tf.sih ieodhlrC evoms het ppioseot crioednti as 3HCO- ni the B.CR sTuh at ssiuste ehrwe we rea ennragtgei -HCO3 romf CO2 and ened to umpp it out fo eth le,cl lhidocer vosme noti teh cle.lAt het aovliel hrewe we ende ot uppm HCO3- kacb iton teh BCR ot tunr ti toin OC2, ldrichoe evmso uot of eth clle.

trehO nser:was

  • 3P,2GB llwi bdin dna aetlbzisis oxbymonaiehgdel nmgkai it elss tttaaedcr ot enxgy,o gthinisf eht bnlohiemga osiitnsoasid ucevr trhig.
  • ixemleoaonDyghb ahs a iehgrh acapctyi ot fmro bohebngmiaanircolma
  • yblhneaoeoDimxg ash a rhihge pKA athn xlmboygeahion hs(ti is hwy ti acn etapcc eyndrhog ions omre idrayl)e
  • itoenCmoitp orf idningb iste is not a rajmo cemanihsm rof eht tayibli to yarrc O2C as msot CO2 is rredi"ca" yb neicnvsroo ot HO3-C
  • tiNcir deiox ginndbi si ton a nsmcamehi of OC2 a.rcyr
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