NBME 15 Hypervolemia (NBME Answers)

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nbme15/Block 2/Question#31 (reveal difficulty score)
A 24-year-old woman with Marfan syndrome ...
Hypervolemia 🔍 / 📺 / 🌳 / 📖
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submitted by ∗cheesetouch(249)

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pregnancy causes hypervolemia, and higher blood volume/flow through the heart will increase murmurs (aortic regurg.)

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+2 upvote downvote
submitted by ∗cassdawg(1780)

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Pregnancy causes hypervolemia which can increase the risk of aortic dissection in Marfans syndrome

(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721114/)

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+0 upvote downvote
submitted by ∗chaosawaits(92)

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Wouldn't weight gain increase afterload due to increased peripheral resistance, which also increases AR?

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imgdoc In pregnant women, afterload decreases, regardless of weight change. +

leap1608 weight gain would decrease the preload and in pregnancy the afterload decreases as placenta is connected in parallel with the system. hence weight gain would not lead to accentuation of murmur +

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