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NBME 15 Answers

nbme15/Block 2/Question#40

A 4-year-old boy is brought to the physician by his ...

Cytoskeleton

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Classic picture for Duchenne muscular dystrophy. which is due to deleted dystrophin protein.

From FA: "Dystrophin helps anchor muscle fibers, primarily in skeletal and cardiac muscle. It connects the intracellular cytoskeleton (actin) to the transmembrane proteins α- and β-dystroglycan, which are connected to the extracellular matrix (ECM)"