Classic picture for Duchenne muscular dystrophy. which is due to deleted dystrophin protein.

From FA: "Dystrophin helps anchor muscle fibers, primarily in skeletal and cardiac muscle. It connects the intracellular cytoskeleton (actin) to the transmembrane proteins α- and β-dystroglycan, which are connected to the extracellular matrix (ECM)"

DMD->Deleted dystrophin, Dystrophin helps anchor muscle fibers, primarily in skeletal and cardiac muscle. It connects the intracellular cytoskeleton(actin) to transmembrane proteins α and β-dystroglycan, which are connected to the extracellular matrix.