Alcohol and benzodiazepine withdrawal lead to similar clinical syndromes with increased autonomic activity (tremors, anxiety, sweating, agitation, etc.) because prolonged use of these medications leads to downregulation of GABA receptors, such that removal of GABA agonists (alcohol, benzoโs) leads to relatively decreased inhibitory activity from ligand binding to GABA receptors
Key idea: Withdrawal often leads to the opposite effects of intoxication with drug (Example: Opiate use leads to constipation and pinpoint pupils, whereas opiate withdrawal leads to diarrhea and mydriasis)
submitted by โsugaplum(487)
These are symptoms of acute benzo withdrawl