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NBME 20 Answers

nbme20/Block 1/Question#1 (reveal difficulty score)
A 37-year-old nurse is accidentally stuck ...
Inhibits reverse transcriptase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm

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 +10  upvote downvote
submitted by โˆ—hayayah(1212)

NRTI's are associated with possible side effects of anemia, granulocytopenia, and myelosuppression.

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sympathetikey  Especially zidovudine. +22
fmub  Nucleoside reverse transcriptase inhibitors (NRTIs) block reverse transcriptase (an HIV enzyme). HIV uses reverse transcriptase to convert its RNA into DNA (reverse transcription). Blocking reverse transcriptase and reverse transcription prevents HIV from replicating. +3
meja2  Thank you Sketchy!!- Zelda for Zidovudine <3 +1
athenathefirst  ZDV used for general prophylaxis and and during pregnancy page 203 FA 2019 +1

 +6  upvote downvote
submitted by โˆ—divya(75)

For anyone interested, the current post exposure prophylaxis regimen contains - Tenofovir + Emtricitabine + Raltegavir

Link for PEP prophylaxis following occupational exposure

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