Frontotemporal dementia (formerly known as Pick disease):
Early changes in personality and behavior (behavioral variant), or aphasia (primary progressive aphasia). May have associated movement disorders (eg, parkinsonism).
While this presents very similiarly to Hungtington's, you can differentiate it because in this stem it says "atrophy of the frontal lobes bilaterally" whereas Huntington's has atrophy of caudate and putamen with ex vacuo ventriculomegaly.
chj7Also, in frontotemporal dementia, due to disease of the "cortex", memory/speech/behavioural changes occur early on.
(In Pathoma at the beginning of the dementia lecture, he emphasizes distinguishing between disorders of the cortex vs. disorders of the striatum (ie. Huntington's & Parkinson's) as clinical presentations are easily separated.)+1
submitted by โhayayah(1212)
Frontotemporal dementia (formerly known as Pick disease): Early changes in personality and behavior (behavioral variant), or aphasia (primary progressive aphasia). May have associated movement disorders (eg, parkinsonism).
While this presents very similiarly to Hungtington's, you can differentiate it because in this stem it says "atrophy of the frontal lobes bilaterally" whereas Huntington's has atrophy of caudate and putamen with ex vacuo ventriculomegaly.