welcome redditors!to snoo-finity ... and beyond!

NBME 20 Answers

nbme20/Block 3/Question#6

A new drug has the following effects on the ...

Pathway labeled 'H' (Conversion of Leukotriene A4 to Leukotriene B4

Login to comment/vote.

 +1  upvote downvote
submitted by neonem(306),

Leukotriene B4 is a potent chemotactic molecule for neutrophils. Selective loss of this would have no effect on platelets, mast cells, or endothelium - these are more responsive to changes in TXA2, complement/arachidonic acid, and PGI2, respectively.

kernicterusthefrog  FA says: "Neutrophils arrive B4 others" +1  

Rule out anything leading to LTC4 because mast cells release LTC4, LTD4, and LTE4 in Asthma to increase bronchial tone.

+/- hungrybox(318),