Familial adenomatous polyposis is an autosomal dominant mutation. Thousands of polyps arise starting after puberty; pancolonic; always involves rectum. Prophylactic colectomy or else 100% progress to CRC.
Autosomal dominant diseases have, on average, 50% chance of being passed down to offspring.
sympathetikeyI would say this is Lynch Syndrome (APC is usually thousands of polyps) but lynch syndrome would generally have a family history of other cancers as well, so you might be right. Either way, both autosomal dominant so win win.+12019-05-31T22:37:41Z
smc213uptodate states: Classic FAP is characterized by the presence of 100 or more adenomatous colorectal polyps+2019-06-25T05:28:32Z
dickass@sympathetikey Lynch Syndrome is literally called "Hereditary NON-POLYPOSIS colorectal cancer"+2019-09-16T11:30:02Z
to snoo-finity ... and beyond!
submitted by hayayah(399), 2019-05-15T22:19:36Z
Familial adenomatous polyposis is an autosomal dominant mutation. Thousands of polyps arise starting after puberty; pancolonic; always involves rectum. Prophylactic colectomy or else 100% progress to CRC.
Autosomal dominant diseases have, on average, 50% chance of being passed down to offspring.