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Retired NBME 20 Answers

nbme20/Block 3/Question#24 (reveal difficulty score)
A 2-month-old girl is brought to the ...
Thyroid function tests ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—hayayah(1212)
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Patient has congenital hypothyroidism (cretinism). Findings: pot belly, pale, puffy-faced, umbilical hernia, macroglossia, hypotonia, poor brain development (MC cause of treatable mental retardation), large anterior fontanelles.

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whossayin  how can you differentiate the symptoms of cretinism from Down syndrome? +
step1soon  @whossayin Down Syndrome: upslanting palpebral fissures, atlantoaxial instability, bent little finger, congenital heart disease, displacement of the tongue, excess skin on the back of the neck, flaccid muscles, hearing loss, immune deficiency, low-set ears, mouth breathing, obesity, obstructive sleep apnea, polycythemia, seborrheic dermatitis, single line on palm, thickening of the skin of the palms and soles, thyroid disease, or vision disorder +3
ally123  I was confused about why the infant was jaundiced, and found this: "Hypothyroidism causes decreased rate of bilirubin conjugation, slows gut motility and impairs feeding, all contributing to jaundice." Source: http://www.pathophys.org/neonatal-hyperbilirubinemia/ +9



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submitted by โˆ—dickass(127)
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...migrant workers ...has not received routine medical care ==> she was not screened for hypothyroidism

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lovebug  Wow good point! :D +1



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