NBME 20 Formation of complexes with mineral ions (NBME Answers)

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submitted by laminin(14),

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almondbreeze FA 2019 pg. 192: Do not take tetracyclines with milk (Ca2+), antacids (eg. Ca2+ or Mg2+), or iron-containing preparations b/c divalent cations inhibit drugs' absorption in the gut +1

fatboyslim This is also why tetracyclines are teratogenic and should not be given to children because tetracyclines chelate with the calcium in the teeth and cause tooth discoloration and inhibit bone growth in the fetus/growing child (Source: SketchyPharm) +

kevin just remember fluoroquinolones also are prone to chelation. you know it's gonna pop up on the real one +