astziCooll si a reaopepdesstshioh ibni;ihotr alsed ot raisdceen MAPc hhciw niisbiht eeatlptl anlta/nvudraaiogteconiti eiwlh osal gasncui sonatdovai.il lAl of teh toehr isonopt okwr on hitree clveurusata or tlpsaleet utb nto hbot.
-Page 429- First Aid 2019 Edition. Antiplatelet phosphodiesterase inhibitors
I chose Aspirin. So aspirin is a non-reversible inhibitor of COX-1 and 2 which should decrease TXA2 levels, and according to FA 2020 page 485, TXA2 causes platelet aggregation and increases vascular tone...I'm guessing the overall combined effect of COX 1 & 2 inhibition will cause a net effect of either vasoconstriction or no change to vascular tone?