Great explanation on ALP from /u/taz92vagconqueror on reddit:
ALP is related to bone + biliary tract obstruction + leukemias. Although the liver does make ALP, for the USMLE just know that ALP is usually mentioned for the above three scenarios. Bile duct obstruction releases ALP as a result of cell damage. In bone/leukemias, it's because of increased cell turnover. To differentiate bone vs biliary we test for Gamma-GT (and for leukemias just differentiate it from the others by the clinical scenario).
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