NBME 20 Increased osteoclast maturation and activity (NBME Answers)

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Retired NBME 20 Answers

nbme20/Block 2/Question#7 (reveal difficulty score)
A 30-year-old man comes to the physician ...
Increased osteoclast maturation and activity 🔍 / 📺 / 🌳 / 📖
tags: endo PTH

+11 upvote downvote
submitted by cafeaulait(11)

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I ieelveb sith estm mya be nngiierrf MNE 1 emdoyrns - eliossbp tgairsmoan i(tppce rucel aesdise xd,) praahidrtoy oaenmda, nad yaritiptu edoaanm c(uansig S)I.ADH B,tu uyo dont' ende to vene wonk tihs to egt sthi hrgit - sutj agikns teh eeftcf fo hhgi TPH on eth tmssye - acsesu ecanidrse tooscealts aiyttvci sa lwel sa o.tmtaaiunr

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fatboyslim heT pyssmotm of iths apettni rae deu to acpleicmyaehr o,et(sns on,esb ,agrnso ENRTOSH re[cedinas i}ds,erusi nda trhpccisayi .voeeorst)n arecaiHmpeycl nac loas acues ppciet ecrul aise.dse So eth piryram plgoyohta si rprhiytadao ps/anldrmyapaoeieah ugsanic eth aeleiycpmchra +6

beetbox Dseo oeynan nowk 'thwsa pu wtih het o'n msbnileotiraa in erushmu X'rdDyia? eyht utjs howrt htta in fro no oarnse? I tgo odkheo no ,ti I ttghohu rhete wsa on ineedrsca coaslosett .i.aycttvi. erioshwet teh lacotric obsen woudl hvae ebne ydold ihtn or oigtehmns +4

topgunber MNE 1 - P P P . tardoaihPry, gsaaparcnirs(net in hsti ,csa)e iuytirtap snoi.le tno key ot gnewasirn hits ot.u qtpsnei cesom hiwt smympsot fo ramcyaepelchi, a,onms aosgn,r trhoesn n,iee)gp( hcysp eoLov eksor.not ta hpt adn cimcul.a we ees ighh ca nda ighh pht. eW okwn htat hihg clcuiam wluod elorw h.t..ithps namse het gihh climcau saw edu to het ihgh pth (.e.i oihyadratrp eoemo nandsQ)taiu is caullyta gainks: whta aer het efsctef of T?HP ,a ,c eoipptso fo TPHD dna E i dveeilbe 'earnt eetdlra to PosdHS n-BTu mesgtniho ielk het ehsisetpngoa fo hh rmdptuiyasadrpFooispye-e ew ndtiileeyf wokn atth PTH eiaresnsc aC , os by riecainngs stlestcaoo ucyrititataitmoan/v ouy irebltae ciluamc tion the o.odlb shit si the sbte srwen.a +3

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submitted by ∗laminin(18)

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nac nmeseoo enailxp yhw ti sasy he hsa na cian''tt PHT t.notnaorcci.e.isn it ot tel su knwo taht teh HTP oncactorntein si a suelrt of ?nlaoyaghdtpo wats'h his xd? takhns!

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yotsubato I erwsa ythe mkea up semo fo isht .tffsu Liek ahstw up whit the t,htisr ntuiroa,ni nda itecpp lurec sessia.ed +9

redvelvet eharepyccamli nac uaecs hcpnregeoin dbeiesta ;idpissnu os sritht, uroni.inta lecahyiepmcar acn slao secau etcpip celur eeia.ssd His yptmmoss are lla otbua yamhlcaecerip edu ot pihrrayaiemstoyd.hpr +4

namira yealHcipacer"m can cusae arlne insuoydfctn chsu as rcoehnpnegi eatbdise sduniipis NID)(, tub het scnmhsaemi lgyuernndi cnarlieueaechdd-yimcp NDI are otn llwe ooes.d"rnu tdt/n/1w3.atd3rS02fiaxt.-etrl)8itct7n/e5ertslew59/ln0u(ngko84hl0-o6:-iyiawp0/ +2

dulxy071 Why ctn'a het retrcoc aewsrn eb C) chiwh ospnti stdowar ealrn u,firela wichh aym dael ot dcreyosan rhsrmidyehryaappiot gvhina the amse rsesltu I eileveb +2

pmofmalasia ehT ceorynsda tiyrpieapyhahdrsrom ni relna refilau si ued to slso of iamccul ni eth ucfnignoontin-n yi.edkn nI siht qsentuio eth liamcuc was a,eldeevt so ouy cna relu tou nlera efral.ui +1

sars ierlpe-aHcmyca cssaue snesot u(cclmai ),tensso gsnaro p,otci)ia(nonts hrnseto r(siceadne utaiiro,)nn bosen (edcaisnre oaotceslts avoitan,t)ci dan ihspraicyct vseoetron .seepd)orisn( +1

epiglotitties aostyb@out olsa as soomene detneionm in oethnar ,ocnmetm i tnhki 'reeyht iitngnh htat eht px thmig heav M1.EN adrtoriyhaP shrip-ylapea cmilcryhap,eae atuypitri ad-noema AHIDS irrut(ns,iot+a)tnih nda cainaptecr to-mru togmsinara ecpi(pt lurce edi)eass +

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submitted by killme(14)

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heT coecnpt egbin dttsee is t"wah oeds TPH od that alesd to " ahierpcmacely3Vj/nogm/t...iibc/shP/K:idapgebstp

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yotsubato gu,h htubil.ls I saw ngryit ot fruige otu na luaact dieasse rsecops her.e +7

rio19111 sit pmryiar paemipyhrhsoidtyrar acesud yb rordtayihpa .ndaeaom diiadton of hte ipcpte ulcre usgetsg oelrZngli -&t-g;- NE1M ub t eonn of taht si mpi acsuebe ts'ath ton htaw yhet ear kai.gsn lAl hyte are ngsiak rfo si teh nucointf of .THP +3

topgunber EMN 1 - P P P . yriatao,dhrP sr(raspnnacgtiae ni hsit ),seca ryipttaui enil.os ont yke to srgeninaw isth to.stqupeni mceos hwti pmtssomy of ealrehiapccy,m asmo,n sanorg, senhrot g)n(,eiep pyhsc oesokrL e.oontv ta tph adn lcu.maic we ese hihg ac nda gihh thp. eW wnok tath high limacuc uowdl oerlw phits..ht. names teh ghhi iccmula asw deu ot teh ihgh tph i(e.. apidhrytaor mtueeo )oaidsnanQ si ataclyul nksag:i hwat aer the efctsef of ?PHT a, c, tesioopp fo H DPT dan E i ledebeiv nt'are telerad to BTsn PudSHo- ognihmtse iekl the taesesnopgih fo pmspi-prdho ysheuyieardaFto we dyelteifni kwon that PTH nrseesiac aC , os by recgniinsa oetlssaoct vromttauayitnt/aici uyo betielra laicumc noit teh odlo.b ihst si teh tbes wenras. +1

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+2 upvote downvote
submitted by ∗sympathetikey(1600)

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nI ndaidito ot HTP = atetloocss tcviiyat = ncraiedes aucicm,l ihts rneops could laso be bgiihinxte ymmtosps of .NEM1

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topgunber MEN 1 - P P P . Phrraaitod,y tanscangeripasr( in sthi aesc), ttaryipui .oilnse not yke to rwneagins ihst u.tis etpnqo oemcs twih smmpsyto fo iery,eaplacmch mosa,n g,oarns onerhst p,(g)enie hcpys kots eoeorL.onv ta thp nad cuc.lami ew ees hihg ca dan ighh p.ht We knwo taht ihgh icalucm ulwod wroel .t.hs.tpih neasm eht ihgh iucacml aws ude ot het ghhi thp ..i(e otphaairdry da )eatosmionnQue is lultacay sik:agn hawt era hte fetefsc of HPT? ,a ,c eopitsop of TPHD nad E i eilvebde et'nra delarte to suoB-HPTdS n nmteogsih keli eth sashpieoengt of yrsseayp-ah tdieoudhpiFprom we finityldee nkow htta PHT sraceeins Ca , os yb anrisngcei ecotlsasto attt/toiivaimcyurna ouy riteeabl mauiccl ntoi eht l.odbo ihst si het btse ean.rsw +1

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+1 upvote downvote
submitted by rio19111(16)

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its rmayirp shryrhmiaypteaiordp dcasue by aaodpiytrhr odmea.na datindoi fo het picept cerlu sgsegtu elogrZnli t--g&;- MEN1

ubt neon fo tath is mpi bueeasc htast' not hwat yeht ear .nksgai llA eyht are iagnks for is the tonfucni of PTH.

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rio19111 tsen,oS raos,gn hse,tron pshcaiitycr evoeronst gt-;-&- mystmpos +1

topgunber NEM 1 - P P P . trya,Phdroia siaartsan(egprcn ni siht ,a)ces ryptauiti lsnoe.i not key to nrnaiegws tshi nuipto.se qt omsec ihwt ymtsosmp of apyicrmahlc,ee ,snoam a,ornsg rhtenos pg,een)i( chspy kLroste. eooonv ta thp dan a.culmic we ees ihhg ca adn hhgi pht. We nwko tath ihgh ialcumc udlwo lrowe sihhtp...t names eht hhig calmciu saw due ot het ihgh tph .i.(e oatryipahdr )tndoseuiQonae am is lyacatlu :isngka tahw ear the fetecfs of HP?T ,a c, poeosipt fo HD PT adn E i eivbdlee rnta'e ltdaree ot H TPSdn-Bsuo tsihmoegn kile het aihsgsepteno fo aaprFroieupsydy-hhisdop tem we ftiilneyed nkwo ahtt PHT ricnssaee Ca , so yb enrcasgnii oaleocsstt attayviinomiutt/car you irtalbee mcialuc oitn hte o.oldb hits si teh setb ase.nrw +1

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submitted by ∗nwinkelmann(366)

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seoD nnaeyo wnok eht einasigcncif of ooemnytc loimytt?i

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submitted by arthur_albuquerque(1)

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Wath hleped me to ewrnsa itsh eon uqtei leiays swa eht iwfoonlgl atrl:ieoan

pcHlamairceye + gihh HTP ;g&-t "rmyrapi piyretrpryhsoadma"ih

oHw do high TPH eadl to cl?cehyarpiaem arnensIcig ctetsolaos tyca!iivt

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submitted by ∗topgunber(68)

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NEM 1 - P P P . ytoh,arPdira encsipg(arasrtna ni itsh esa)c, tipauryti .islone otn yke ot geawnnrsi shit e.ituqsno

tp meocs twih sspoymmt fo ,riamyphecleac namso, sarog,n strnheo (pei)egn, pchys osrev.etno

Lkoo at thp dan muacli.c we see ghhi ca and high pth. eW wonk taht ihgh cucailm wuold ewrlo hs.i..tthp emans eth hhig cmclaui swa eud to the high pht .ie.( ryoihrpdtaa a)dmaeon

eQtsnuio si llayactu ksg:ian wtha rae eht ffeecst of PTH? a, c, isppeoot fo THP

D dna E i bveelied 'ertna etdelar ot HPT

ouSs-dBn omihsteng kile hte htsapoinsgee of ohapysrmtyerohipisudapde

F- ew edeiltiyfn nkwo taht THP aessrenci Ca , os yb rningiacse cootesslta /ttvnriiyoataauctmi ouy eteirabl amccuil iton teh doolb. shti si eht estb w.esran

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