NBME 20 Increased osteoclast maturation and activity (NBME Answers)

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Retired NBME 20 Answers

nbme20/Block 2/Question#7 (reveal difficulty score)
A 30-year-old man comes to the physician ...
Increased osteoclast maturation and activity 🔍 / 📺 / 🌳 / 📖
tags: endo PTH

+11 upvote downvote
submitted by cafeaulait(11)

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I bveliee hits stem mya be rfnineirg MNE 1 srydnemo - slesipbo snaamtirog p(ietcp eulrc eaiesds dx), aradtyorphi oamdn,ea nda yairtiutp moednaa uac(ngis D)HS.AI ,utB yuo 'ntod eedn ot even owkn isth to tge tish thirg - just gaknsi the cfftee fo ihgh HTP on eth tssmye - uesasc acesreidn ttlosasoce ytativci sa lwle sa mu.taniorta

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fatboyslim Teh psommyst of hsit aiptnet rea eud ot ameecahryicpl (n,sotse obs,ne sran,go RSEHNTO eindsca[re reis},udis nad ticypirasch ovt.ee)rnos mrylcaiHecpea nca laos ecsau ptcipe ulcre eeisds.a So hte amiyrrp playhtgoo si torhyiarpad hrsaodame/paneliypa nagsuic teh aepclmcayireh +6

beetbox eosD yoanen nkow wsath' up itwh hte 'on bleasaiotrmin ni shrmeuu ?iyaXdrD' hyte tujs thorw htat in for no ?ansreo I tog doeohk on ,it I tuothhg eterh wsa no narsciede setctoslao ciya...vtit tirewehos eht ltracoci bneso duowl hvae been lyddo thni ro tmnsgoieh +4

topgunber EMN 1 - P P P . ayrPra,ohtdi ngtsas(pienrrcaa ni isth ,sace) iytaptriu so.inel ont eyk ot awsnngier stih .eiqspt tnou soecm tihw yomtpssm of cicpmyrah,eael ,saomn argosn, horsten n,(pi)gee sycph ts rovekoLeoo.n ta thp dan imaccul. we ese ihhg ac adn ghih .tph eW kown hatt ghih aiumlcc dluow wlroe t.ihsth.p. nsmae eth ihgh culciam wsa edu ot teh high pht e(i.. ihrdaoatypr m anasei)toQudeno si atalulyc gansi:k thaw ear het fefsetc of P?TH ,a c, ioptepos of P TDH dna E i eevdeibl nrea't erdlate to TnHSoBs-udP emtnhgsio kile eth poegasehsnit of mpi-rhyd hsupyoerseFpoitada we yfleitiend kown thta TPH cseaniesr Ca , so by inceisargn aetcsosolt utvyttoimiacti/nraa yuo alreetbi ucamilc ntoi eth do.bol isht si eht ebts .rweasn +3

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submitted by ∗laminin(18)

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anc monseoe xplaein hwy it ssya he ahs an 'na'itct TPH nn.at.ccsnoeit.ori it to lte su ownk hatt teh PTH tinncnarotoec is a eutlsr fo ynalp?dgatoho w'ahst ish x?d !hsktan

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yotsubato I aresw tehy kmae pu oesm fo htsi f.tsuf ekiL hatsw pu twih het hst,tri uarii,nont adn tppcei lruec sed.ssaie +9

redvelvet ealahiemcyrpc can uasec ecneopghrin ieadtseb ndui;spis so trhist, nro.utniai arheyemclciap can olas cseau ptpice clure ied.ases sHi tspsoymm are lla taubo ceprilaemcyha edu ot peodhiirtyhmyasr.rpa +4

namira mcli"Hypreeaca nac saceu neral fcinotusdyn chus as egeoinrcphn isedebta siiuspdni )IND(, utb het msehnsciam igydnrlnue eiemarund-lccdpcyehia IDN are tno elwl etod" n.sorduo5920ewhatt.8tl/nynuwoaS0ie.(iigni58rtt63cl:dtw1tlear-0fkslp-7n-/x/e/r4)/03 +2

dulxy071 hWy tan'c het occterr swenar eb C) ihhcw pionts stroadw lnaer li,eafru hchiw aym edal to esoandcry rmsytioeaprarypihdh nvaihg eht msea rseutsl I levieeb +2

pmofmalasia ehT sdacynore rsdarypmpyahheitiro ni aelnr rafilue is deu ot olss fo limucac ni eth ctnfu-nnnoiogin iyed.kn nI iths iounetsq teh imacluc was lde,eevta so oyu cna elru uot erlan iefarul. +1

sars ceHaec-mlriypa sauecs ntseso lau(mcic es,)nost saorgn oit,nscton()pai hnoster ancdsie(er a,nitnurio) esnbo ienasdcr(e oslaoetcts iian,ott)vca dan cyairhpisct osoetervn )nroepi.ss(de +1

epiglotitties tbatuosoy@ laso as emoneso oeeinmtnd in eoanhrt mtncoe,m i iktnh re'eyht ghnniit thta het px hgmti have E.M1N Poryhiratda apirhl-ypsae cerpymaeila,hc yiraitupt -oednama DAHSI roirttn(,na+is)ihtu dna tpaicrncae utor-m nomiaatsrg cppit(e culer idaesse) +

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submitted by killme(14)

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Teh ptnocec bigen ttedes si htw"a deso TPH od hatt adlse to ehrp"icec ylmaahVcpdi/snaipeisg3t/m/b/...gbotjP:K

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yotsubato ,hug ishltlub. I asw nrygti ot urgife tuo na cltaua sdesiae ssoeprc .hree +7

rio19111 its ymarpir ppytyordehirhaasirm descua yb raydhatprio moe.aand ndtidaoi of the ciptep erclu gsestug legoilZnr -g&t-;- EM1N tu b enno of tath si mip eucbase st'ath tno whta thye rea gin.ska llA ethy rae aknsgi rfo is hte cfutnnio of .PHT +3

topgunber NME 1 - P P P . roirhatPd,ya apeacrtiar(snnsg ni hsit e)s,ac ituayprti i.eolsn ton kye ot seinrngwa shit ep.tnuqt soi cmoes twih styospmm of apceaiymech,rl nas,om ngas,ro nshoret ,e(epgin) hycsp n.korvtosooee L at htp nda clumaic. we ese ghhi ca dan ighh .pht We knwo htat high uclaicm oudwl owelr .s.phitth. nmase het ghhi lcamicu was ued to teh high tph i..e( dropryahati etoQonudiasma )ne is actlaluy igka:ns thaw rea the festfce of ?HPT a, c, opoipest of TH DP and E i eelbvide r'ante erateld ot HSns-oBTud P tesngmohi klie teh ssahepiteong of dsip pisohd-rheFpaaymruotye we iiyedlfnte ownk ttah HPT rnsiaesec Ca , so yb ienicgrasn coaottslse cttttaiarun/avmoiiy yuo arbteeil ucaciml noti the do.lbo siht si hte tebs ars.wen +1

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+2 upvote downvote
submitted by ∗sympathetikey(1600)

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nI itinddao to HPT = oassolttce vtiicaty = racdeeins iccamul, itsh sreonp ldcuo sloa eb niithxgbie tmmyosps of ME1.N

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topgunber NEM 1 - P P P . aPoria,dthry raanscpista(nrge ni ihts c)sa,e auprtiity lnsie.o nto eyk to siawgnern isth .opequti stn smoec ihtw spsyomtm fo ch,eciprmaelya ,msano ,ngosar oehnsrt ,g)(npeie pyhcs Lvtkonor.esoe o ta pht nda alcicum. we see ighh ac nda ghih th.p eW oknw ahtt hgih aumccil dolwu eorwl .pht.hit.s nesam het ihhg cicualm aws deu ot teh ihgh thp i(e.. airdahptyor o)oeQaenanmts diu is layucalt snia:gk atwh rea eht cffeset fo P?TH ,a c, isetoopp of HP DT dan E i lvedeibe 'retna aletder to PBuHndo-Ts S ehgtionsm ilke teh esgenasotihp fo rmddasphpyts-eioayFroupehi ew iidlnyeetf wkon ttah HTP renssieac Ca , os yb riiaescnng atsctoloes tai/titutcmoyanriav oyu bteialer uacimcl oitn eth olbd.o hsti is eth stbe s.narew +1

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+1 upvote downvote
submitted by rio19111(16)

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tis mprriay otpprhdramshyryeaii scaude yb oaitrarphyd medaa.on didnaoit fo the pietpc lcure tgsuseg orlZielgn --&-tg; MNE1

but nneo of ahtt si mpi csuebae thas't otn awth ehyt ear ni.kags lAl ehty era inkgas rfo is the focitnun fo PT.H

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rio19111 ,snteoS on,args hotnrse, spcytharcii neosvrote ;t--&g- pytomssm +1

topgunber NME 1 - P P P . hP,yoradtrai arspa(gninctrsae in stih ec,)sa iirttpuay es.loni ont kye ot erwsainng shit qu.nist etop scemo thwi mystspmo of cmepa,irhelyca sa,mon aor,gns enrstoh een(i,)gp chpsy keteosvr Loo.on ta pth dna ilamcuc. ew see ghih ca nad hhgi th.p eW oknw htat high cmiulac ouwdl ewrol ipsht.t.h. nsema eht ghhi cmlcuai swa eud to the gihh pht ..i(e yahaiorptdr oQaneesma)tdi nuo is ayalltuc asgkni: twah rea eht ceetfsf of ?TPH a, c, tooiepps fo THDP dan E i eevliebd anrt'e eadlert to nSdT-ouB PsH sihmoegnt klei hte eiegtsahspon fo -aasryepdoprhieuyohFdmts ip we tlydifinee wkno hatt PTH rseisacen aC , os by egriancins ocoltaetss ta/ancmruviitoiytta uyo bartleie ucaciml iotn eth d.olob tsih is het sbte eaw.nrs +1

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submitted by ∗nwinkelmann(366)

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seoD enanyo kown the sagfceiiinnc fo cntoeyom mttiioly?

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submitted by arthur_albuquerque(1)

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atWh lpeehd em ot nwsera tihs noe eqitu seliya swa het logilfonw roltniae:a

amcpHecyilaer + gihh TPH g&-t; aypmri"r hm"doetraspyrrhapyii

owH do gihh THP adel to yhecpmlariec?a cIenrsgain taossctelo cy!iativt

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submitted by ∗topgunber(68)

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NEM 1 - P P P . ratihPd,ryoa sna(stciagenprra in isht cs,ae) ytituirpa nsel.oi ont eyk to gnnaweris tish i.onqesut

tp cesmo ithw pymmsost of epehcrmialca,y no,asm sroan,g nosehrt enge,)pi( cphsy tosorenv.e

okLo ta hpt and .cacmlui we ese ighh ca nad ghhi t.hp eW okwn htat high amcuilc oudwl rowel pihs.tht.. samne het ihgh aicucml wsa deu to the hhig pth e..i( rharodayitp n)daoema

isetQuon si llcauyat gaikns: waht ear eht cfsteef of PTH? a, ,c oopsipet of PHT

D nda E i ileebvde ntar'e dltraee to HTP

Sndu-osB toesinhmg ikle teh sanihgpteoes of rhameapodotryipeuyhpssdi

-F we iyiefndtel okwn htta PHT iseanrcse aC , os by snergnciai scealotost vatirtinoiaatuctmy/ oyu eatbirel mlacciu tion eth lobod. itsh is hte esbt sw.aern

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