need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)
NBME Free 120 Answers

free120/Block 1/Question#5 (reveal difficulty score)
A 24-year-old woman comes to the physician ...
Vascular endothelial growth factor ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

 Login (or register) to see more

 +3  upvote downvote
submitted by โˆ—mamed(25)

Formation of granulation tissue (Day 3-7 of healing): Fibroplasia leads to the synthesis and deposition of type III collagen. Growth factors (ie- VEGF) from fibroblasts and epithelial cells promote angiogenesis. (Credit- Amboss)

 Login (or register) to see more

 +0  upvote downvote
submitted by โˆ—an1(114)

"pink, soft, granular, edematous wound" describes granulation tissue, which appears around day 3 and last several weeks. At this time, there is also an abundance of fibroblasts, endothelial cells (which contribute to angiogenesis with up regulation of VEGF) and macrophages as well as keratinocytes.

 Login (or register) to see more

 -1  upvote downvote
submitted by โˆ—bwdc(697)

VEGF is a major tissue growth factor activated by injury, cytokine release (infection, inflammation) and hypoxia that promotes angiogenesis and also increases vascular permeability (hence the edema). This increased permeability aids in the movement of proteins and white blood cells to the site of injury.

 Login (or register) to see more

Must-See Comments from free120

sugaplum on It is a polymorphism
bwdc on Elaboration of proteases and urease with ...
bwdc on Hypercoagulability from advanced malignancy
bwdc on Ribosomal assembly
bwdc on Aspiration
bwdc on Amygdala
imnotarobotbut on von Willebrand disease
bwdc on Trinucleotide repeat expansion
bwdc on Mediation of cell entry via a fusion protein
bwdc on Metabolism
bwdc on Basement membrane
melchior on Aspiration
hungrybox on Immune complex deposition in tissues
aejinkim on Decreased activity in the enzyme that ...

search for anything NEW!