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Retired NBME Free 120 Answers

free120/Block 1/Question#39 (reveal difficulty score)
A sexually active 23-year-old man with ...
Antigenic variation ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—bwdc(697)
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N. gonorrhea can change its pilus, which is responsible for adhesion to host cells and the main antigen to which the host mounts an immune response. Neisseria gonorrhoeae is able to switch out different pilin genes, and for this reason, prior infection does not confer long-lasting immunity.

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t123  to emphasize, N. gonorrhea commonly uses phase variation as opposed to genetic changes. +3
despistada2022  N gonorrhea can change its pilus, which is responsible for adhesion to hose cells and the main antigen to which the host mounts and immune response. N gonorrhea is able to switch out different ???? (pili?) genes and for this reason, prior infection does not confer long lasting immunity +1



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