share email twitter ⋅ join discord whatsapp(2ck)
Free 120  NBME 24  NBME 23  NBME 22  NBME 21  NBME 20  NBME 19  NBME 18  NBME 17  NBME 16  NBME 15  NBME 13 ⋅ Step 2 CK Free 120  Step 2 CK Form 6  Step 2 CK Form 7  Step 2 CK Form 8 
search for anything NEW!score predictor (β€œpredict me!”) NEW!
NBME Answers

free120/Block 0/Question#10 (reveal difficulty score)
A 22-year-old woman comes to the office ...
CD28 on T lymphocytes ⟶ CD80 on epidermal Langerhans cells πŸ” / πŸ“Ί / 🌳
tags:

Login to comment/vote.


Must-See Comments from free120

sugaplum on It is a polymorphism
benwhite_dotcom on Elaboration of proteases and urease with ...
imnotarobotbut on von Willebrand disease
benwhite_dotcom on Aspiration
benwhite_dotcom on Amygdala
benwhite_dotcom on Hypercoagulability from advanced malignancy
benwhite_dotcom on Trinucleotide repeat expansion
benwhite_dotcom on Basement membrane
benwhite_dotcom on Metabolism

 +7 
submitted by fullmetalapathist(7),
unscramble the site ⋅ remove ads ⋅ become a member ($42/month)

DC80 si salo kwnno as 7.B usenoitQ si iasnkg if uyo know tath D2C8 llecT-s() ittacsnre hwit B7 (A)CP as a ly-mooacutsitr sgailn ot tateiavc teh -elT.lc

sokoL ilek eth ipcteru si darnitsnomegt otatcnc steiamitdr (ude to rhe retcne use of nwe hria )eyd ihwhc si a tyep IV SRH

I uslauyl mebmerre htat B7- si on hte Blcel- a(n PC)A

melchior  Reminder: CTLA-4 on T-cells also binds to B-7, and the effect is opposite that of CD28 (inhibits T cell activation) FA 2020 pg 222 +1  
mmizell  CD40L on T lymphocytes-> to CD40 on Langerhans cells is true association but doesn't answer the question because its co-stimulation induces B cell proliferation, not T cell proliferation. +3  



 +1 
submitted by βˆ—aaftabsethi1(8),
unscramble the site ⋅ remove ads ⋅ become a member ($42/month)

anC aeonyn tlle ohw a aihr dey fdtfeeca her mfreaor ?

vetafig692  lmao good question! +1  
chaosawaits  if you're asking that question, you're not ready to see what the pubic region looks like now +  



 +0 
submitted by βˆ—an1(72),

History and image are a type 4 HSR. This is T cell induced. Cd40L --> Cd40 is T cell --> B cell CD28 (on T cell) --> binds to APC's (including Langerhans cells); CD80/ 86/ B7

Options with ICAM, I immediately crossed out because they're associated with margination and rolling, etc. CD45 isn't mentioned in regards to T cells (or anywhere I might add). Leaving us with the 2 options I mentioned above ^




 +0 
submitted by βˆ—handsome(1),

FA 2020 pg 103 there's a diagram where you can see binding of B7 protein (CD80/86) ---CD28 as part of T cell activation.

Note: Langerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin.




search for anything NEW!