In an asthmatic response, mast cells lead to generation of leukotrienes C4, D4, and E4 (early-phase reaction)
I believe this is aspirin intolerant asthma. Aspirin inhibits cycloxygenase. This leads to more shunting of the arachidonic acid to the leukotriene pathway (excessively), which leads to a bronchospasm.
Aspirin-induced bronchospasms can occur in aspirin intolerant asthma occurs more in adults. Additionally, she experienced this previously with ibuprofen (another NSAID that inhibits cox).