I believe this is aspirin intolerant asthma. Aspirin inhibits cycloxygenase. This leads to more shunting of the arachidonic acid to the leukotriene pathway (excessively), which leads to a bronchospasm.
Aspirin-induced bronchospasms can occur in aspirin intolerant asthma occurs more in adults. Additionally, she experienced this previously with ibuprofen (another NSAID that inhibits cox).
submitted by โaakb(41)
I believe this is aspirin intolerant asthma. Aspirin inhibits cycloxygenase. This leads to more shunting of the arachidonic acid to the leukotriene pathway (excessively), which leads to a bronchospasm.
Aspirin-induced bronchospasms can occur in aspirin intolerant asthma occurs more in adults. Additionally, she experienced this previously with ibuprofen (another NSAID that inhibits cox).