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Retired NBME 18 Answers

nbme18/Block 3/Question#25 (reveal difficulty score)
63 yo man, 2 weeks of fullness in left upper ...
Myelofibrosis ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +16  upvote downvote
submitted by โˆ—amirmullick3(76)
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Tish nitpeta has a dyr pta, hiwch si nese ni ybsloiriemfos nad asaptlic ia.nmae Teh nlaaombr BCR rae sotm iyekll yscrdtceao eo(rpratd l)c.les

AML olwud ahev auer rdso nad myna tcaincrigul so,labsymtle ubt orn anlbarmo B.CR

LM,C deefind yb het 2[;9]t2 dlhliPiapahe mmro,hcoeso lwli avhe mnay meaurt adn gitnmura cnueagsytolr, with a wol LPA ascbuee htsi is otn a mduioeelk ei.nrcato

lotimeyysoeDicp msydrneo is teh sema as a ltsayysdopsecilm dye,msrno cwhhi era a pruog of cncsrea whit miteumra RBC ni the nobe aowrrm htta do nto ebeomc erta.um d/n:phpangw_/ok..ii/siayleewsMtsmleokeprroidticytyd/is

tniesslEa moatyrieohbmhct chhiw( is otn essetalin lpeoti)hcyyam si jsut a rrae crncae hiwt gihh lltpaeest, hchwi esnpstre whit bnmaoral lbodo ntltogci, alidneg to isro,bshotm ,erktsos and P.E

tiPaoyhylmce aevr sah revy elrag BCR mssa nad wol PEO edu ot gnveitae kedcbe.fa tI si deu ot a AKJ2 aintmuto dna aslo sha high WCB dan lel.aetstp uOr tnatpie is cen.ami

./omwhlucie.ewmt/spuv/btye:wouslt

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 +1  upvote downvote
submitted by โˆ—dorsal_vein(47)
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yrD pat + vaimsse lneglepysaom + mlaornba BsRC is ilcascs rof yoisiefmsbolr

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 -1  upvote downvote
submitted by โˆ—amirmullick3(76)
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ihsT patient sha a yrd pa,t which is nsee ni syoseoilrbfim and alpicsat maiTen aeh. lbarnaom BCR rea otms ekyill rydatecsco oed(arrtp e).lcls

LMA doulw eavh aeru osdr dna anmy uitircncgla eblos,smlayt tub onr mbraanlo M ,.CRCLB dneifde by teh 922;t][ hiaeldPaplhi hr,soceomom will vaeh ynma aumret adn gmuanirt cselyoarnt,gu thiw a low APL seabuec stih is otn a likemdoue tyncamlirotDypcsoe ieioe. meodsryn is het same sa a yssltlymdpoaiesc syeo,mndr hchiw ear a ropgu fo eacncsr wthi iaetmrum CBR in eth eonb awrorm taht od ton ceebmo r.utm eas/li/:dMtykwaedsleho_ns/wrspntoieariimpcdiikey.y/gtop.ta ienElss hheymoorcaibtmt hwih(c si tno inseleast ltymcopiayh)e si tjus a erar ercnca twhi high eetlptasl, ihhcw pnetesrs wiht omnblaar lbdoo gtc,itnlo ilngdea to ,isrbhmotos sseorkt, adn imeo.ytPchaEl Py rvae gp( 46)6 sha reyv glare CRB smas nad lwo PEO due ot etaiveng .acbkdefe tI is eud ot a J2KA nuamtoti nad aols sha high WBC nad pslt.etlae rOu apnitte is nicm.ae

bv/./pumlwuysowuhl/eteotwesmt:.ci

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 -1  upvote downvote
submitted by โˆ—amirmullick3(76)
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ihs ettpina hsa a dry ap,t cwhhi si eesn in byiorofmiesls nad picatasl ae.iamhn Te ranbmaol BRC rae smto leykli eoctcdaysr ra(dperot c)lsle.

MAL ldowu eahv euar rdos adn amyn ngriliaucct ysasltel,mob but orn nlamrabo .RCB

,LCM einddfe yb eth 92t];2[ pPliheailadh chooe,rsomm lliw vhea mayn rmaetu adn iatrgunm tlgysencrou,a htwi a owl LPA acbeuse ihts is nto a imkeludoe ret.aionc

slciytDeoiomyep mrsodnye is the mase as a cosmeiptldyyslsa senrmoyd, whhci are a uogpr of ecasnrc hiwt taiuremm CRB in teh oebn waorrm hatt od ton ceeobm utm.rae.dyilotpirlp:idks_eoicpisMrngy//nwos.tiaateheed/mw/syk

eiEslanst mmottohyiearchb ihhwc( si otn nesiaetsl omycpitheyl)a si juts a rear ccraen whti ihhg talsetpe,l hhwci enestrsp hwti oanlramb oblod itclotgn, enadlgi ot hsir,osbmot ,sksetro dan PE.

Polheaiyyctm rvae sha yvre legra BRC sams and wol EPO eud ot tgieaevn dbeefkca. tI is eud to a KJ2A moautnit nad laos sha gihh BWC dan espeat.tll ruO naietpt si mec.ina

euiu.:svot.upmttoemhl/ew/ycbww/ls

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