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NBME 18 Answers

nbme18/Block 1/Question#11 (reveal difficulty score)
67 yo man, fine resting tremor in both hands
Alpha-synuclein ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: neuro repeat

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 +15  upvote downvote
submitted by โˆ—wishmewell(59)
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I saw ndesuocf wenteeb A-hpal yeinnlSuc nad uT.a Thsi nptiate has kinospsrna desaisse nad tshu we wluod ese Aahlp

aTu is esen in sitatnpe thiw ikcPs ssae,dei aka Forelptonamtro teieanmd DNA eizrmlashe ed.sseia pe ga 504. AF 8102

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baja_blast  FA 2019 p. 508 +
jbrito718  The gross image also shows the medulla, where you can see some darkness around the edges, reprentative of the substantia nigra which is affected in Parkinsons. Another hint +1
epiglotitties  *The gross image shown is of the midbrain, the image on the left was from a normal px and on the right our px with Parkinson's. Comparing his gross specimen to the control we can see depigmentation (represents the loss of dopaminergic neurons) of the substantia nigra. +
namesthegame22  Amyloid plaques and abnormal tau accumulation are pathologic markers of dementia, Alzheimer type. Amyloid plaques are extracellular protein accumulations, while tau forms intracytoplasmic and extracellular protein tangles. +

 +7  upvote downvote
submitted by โˆ—andro(269)
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