NBME 18 Alpha-synuclein (NBME Answers)

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NBME 18 Answers

nbme18/Block 1/Question#11 (reveal difficulty score)
67 yo man, fine resting tremor in both hands
Alpha-synuclein 🔍 / 📺 / 🌳 / 📖
tags: neuro repeat

+15 upvote downvote
submitted by ∗wishmewell(59)

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baja_blast FA 2019 p. 508 +

jbrito718 The gross image also shows the medulla, where you can see some darkness around the edges, reprentative of the substantia nigra which is affected in Parkinsons. Another hint +1

epiglotitties *The gross image shown is of the midbrain, the image on the left was from a normal px and on the right our px with Parkinson's. Comparing his gross specimen to the control we can see depigmentation (represents the loss of dopaminergic neurons) of the substantia nigra. +

namesthegame22 Amyloid plaques and abnormal tau accumulation are pathologic markers of dementia, Alzheimer type. Amyloid plaques are extracellular protein accumulations, while tau forms intracytoplasmic and extracellular protein tangles. +

+7 upvote downvote
submitted by ∗andro(269)

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