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NBME 18

nbme18/Block 1/Question#13

10 yo boy, nosebleeds and easy bruising

Antibodies directed against the glycoprotein (Gp) IIb/IIIa complex

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submitted by match95(3),

Immune thrombocytopenia (FA 2017, pg 405) - causes destruction of antibody-platelet complex by spleen leading to decrease in platelet QUANTITY and increased megakaryocytes on bone marrow biopsy.