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Retired NBME 18 Answers

nbme18/Block 3/Question#9 (reveal difficulty score)
35 year old ,precursor to ...
succinyl CoA ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: antiscrambler

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submitted by โˆ—cheesetouch(250)
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Dx is porphyria cutanea tarda. The deficient or defective enzyme is uroporphyrinogen decarboxylase. At the start of heme synthesis, succinyl CoA and glycine combine to form ALA (via ALA synthase), the very start of heme synthesis.

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