This is describing Langerhans cell histiocytosis (FA 2019 p. 426). This disorder presents in a child as lytic bone lesions and skin rash or recurrent otitis media with a mass involving the mastoid bone. Cells express S-100 (mesodermal origin) and CD1a. Birbeck granules (tennis rackets) are characteristic.
anechakfspbRemember, Langherhans cells are a type of dendritic cell+6
j123I thought s-100 was Neural crest cell origin, not mesodermal origin+1
anechakfspbYes, you are correct. I was copying straight from FA 2019. I'm not sure why it say mesoderm. +
submitted by โanechakfspb(77)
This is describing Langerhans cell histiocytosis (FA 2019 p. 426). This disorder presents in a child as lytic bone lesions and skin rash or recurrent otitis media with a mass involving the mastoid bone. Cells express S-100 (mesodermal origin) and CD1a. Birbeck granules (tennis rackets) are characteristic.