,itrFs I neoesard atht XOH ngsee edco orf rpnisnttairco otcasfr deeedn ndgrui mnesiyrbesgoe ,1(F0A29 .59.p8)
t,exN creiacvl irbs aer lorbmaa.n The isbr aer ssduppoe to rstat at eth ohtra.x ,oS XHO ed(eend rof giwrnog sgnith gunrdi bngeoeims)syer olhsud be rsdsxpeee ta eth rhcotcai vllee (ei lacaud ot alvcicre lve)e.l
I was so lost when I saw this. But I was able to break it down and figure out what's happening.
HOX is transcription from Head (cranial) —> Toe (caudal)
I think of this as “HBO is Sex from Head to Toe”: HBO shows have a lot of nudity and what not, the sex helps me think of HbO + seX = HOX; it's for arrangement from the head to the toe.
One of the cervical has become a thoracic looking segment. So we have replaced a cranial segment (cervical) with something closer to the feet/ caudal (thoracic)
So the Hox gene at the top is expressing caudal info when it should be cranial at C7