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Retired NBME 18 Answers

nbme18/Block 3/Question#32 (reveal difficulty score)
X-Ray of a newborn shows ribs associated with ...
Expression of a HOX gene normally expressed only caudal to C-7 🔍 / 📺 / 🌳 / 📖
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submitted by regents(6)
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t,Fsir I enderaso tath HXO eegsn odec rof acroinisrtnpt caotsfr nddeee iunrdg egeobirmesnsy 0AF219,( )..859p

,txeN levcriac ibsr are bnoalmr.a The ribs ear uspedsop ot trast ta het ta.orhx S,o XHO eedne(d orf ogwrnig ghnsit rdunig yeossgn)mbriee luodhs be pdxersees at the rhtaicoc evlel ei( adluca ot accelivr eell).v

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okokok1  to dda tnoo eccrivla isbr bieng mlroanba, hyet ear oufnd ot be eno fo eht esacus of occhrtia tluoet demroys.n +2
kcyanide101  i ma sllit nscodufe rvoe hits esrwa.n Paeles eenomso ulodhs plhe iwth a lfniiyagcr pno.aainlext Wtah smaek reeroxesnvipos of a XHO geen rylaomnl depessxer C7- ?n?w?rgo +
drdoom  :@a1dceiy1n0k oYru rcilaecv tvebrreea odluhs NOT vhea r!isb (eTh kcne lrrabeetv bsdeio ear yllmanro “s!”bslrie) hTe wgtroh fo sirb sa( well sa herot teses“gm”n fo teh )yodb is deogrvne by a vyer isepcal lmaify fo enesg knwno sa hte OXH gs.nee hTe XOH ngee noreiesblps for bri hrtgow uhodls olny get psexdsere “”)rw(ko TRAEF C7. ,If for seom iedwr narsoe, it tesg tunerd on in eth lvtpeeomned of het k,cne you llwi tge nsigth rignwog erehw ehyt t’lsohund eb! +3
drdoom  fI uoy yraell awtn to eavh ruoy hiar onwlb k,acb echkc uto emos gaemsi ofr mnau“tt HOX ”osp:irenesx uechg/s.+hpooht/smmo=xmtitcnmteatbi&r;s=seawpe/xg?.a:psnwrhwc+oolq noj!Ey )-; +



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submitted by an1(114)
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I asw os otsl ewnh I was hsti. tuB I asw laeb to kaerb ti nwod and reuifg tou sw'hat appegihn.n

XOH is ripiatconstnr orfm Head crl(an)ai t—&;g oTe uaad(l)c

I hntki of isht sa OH“B si Sxe fomr eHda to Te”o: HOB wohss vhae a otl of yiudtn nda athw ,tno eht xes lpseh me htkni of bOH + seX = OH;X 'tis ofr rgamtenarne fomr eth hdea ot eth eot.

nOe fo eth viccarle hsa bcoeme a aocihctr oilnogk sgnmtee. So we vaeh cerlpeda a arancli ntemegs )alevic(rc wtih oihstmgne crlose to hte e/fet uaclda coc(ir)tah

So eht xHo geen ta teh otp is srxpsenige ulacad ofin when it duhlos eb aclirna ta 7C

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drdoom  nytseel,lais thsi osintqeu is idisbrgnce a intisotau rehwe hte regona“ sg”nee tog rdneut no ni hte oylwle aera +
drdoom  o,h tis' ton taht teh” Hxo g”ene is nirpgxssee het wongr n,ifo yb teh w;ya ts’i tath eth NGROW oHx eneg si bnieg xdseps.eer hTsi nac ephnap wnhe the wlyietpd xoH eneg lvi(caecr )eaar si uattmde adn os eht aihoctcr oxH egne “aekts vroe” -- enev othhgu rtabmonseilia ,ppeahn stih minmaechs tcrsepto the odyb fomr isigsmn an rtenie tmsngee rtetb“(e to upt het ogwrn tnghi eethr ntah ohnntig at ll!”)a +
an1  orodd@m hwo od ew nokw isth steniuqo saw tialgnk uatbo HOX nisexesgpr eth wnrgo onfi vs OXH bgein orgnw sfeli?t ecSni all eht teroh tsegsmen rae dsumesa ot be .amnlor dlotnu'w ethy be tceaffde too if HXO swa wonrg lla roau?nd +
drdoom  esaBceu HOX egesn cdoeen tinrpaotcsrni f.tcarso hEca XOH riticnrstnoap otfr,ca ni rtu,n norgvse mnay ohrte neseg rsun(t no ,emos rseperess h)rtoes hwhci iredct medevoetnpl of a t.nsgeem Is’t kulyniel a sleign utntaoim in a OXH eegn fps”li“ it ofmr ngdrceiit elavrcci vloeedmeptn to dtigrcnie hcroiact lpeneo.mvdte 'tIs mreo ylklie atth claecvir HXO ft meaecb fscytodannlui osL(“s of ”tFnniocu ,iao)tunmt cwhih eusrlst ni chtrcaoi XHO tf ot ea“kt .er”vo +1
drdoom  ,Oh I ushldo aveh temnnod:ie ehac XOH box si a n/aftrsfateeeieprd ege.n sI't ton lal neo ngee. Ist' a lyfmia of nsgee os a aimtotun ni oen wlil eb etednienpnd of eht tehros. +



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