need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

Retired NBME 18 Answers

nbme18/Block 1/Question#7 (reveal difficulty score)
33-year-old woman, mechanism of action of ...
Inhibits microtubule disassembly ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +3  upvote downvote
submitted by โˆ—okokok1(38)
get full access to all contentpick a username

dont get tripped up on the wording. the answer is "inhibits microtubule disassembly". just remember, "taxes STABILIZE the economy" to remember the moa of paclitaxel and other taxanes.

the other answer choice of "prevents microtubule polymerization" is the MOA of vincristine and vinblastine.

get full access to all contentpick a username
jbrito718  Vinca alkaloids bind and destroy tubulin in microtubules causing mitotic arrest VS taxanes stabilize the microtubules and decrease mitotic spindles. Both in M phase +
kcyanide101  I think of it such that Paclitaxel (taxanes)= taxes, everyone hates taxes...lol. and we are being taxed a lot so they are excessive. +



Must-See Comments from nbme18

feliperamirez on He is medically qualified to drive
anechakfspb on Tubular atrophy
aneurysmclip on Endothelial nitric oxide synthase production
azibird on 24,25-Dihydroxycholecalciferol
famylife on Increased transcription of HMG-CoA reductase
match95 on Plasmid loss
apurva on Antineoplastic
cbreland on Basement Membranes
match95 on Proximal tubule: isotonic; Macula densa: ...
sugaplum on Abnormal migration of endoderm from the ...
amirmullick3 on Myelofibrosis
merpaperple on Primary spermatocyte
wishmewell on Alpha-synuclein
namira on Greening reaction on blood agar

search for anything NEW!