In the question stem the examiners are showing you a picture of a hand with extensive tophus formations (often these appear on the external ear, olecranon bursa, or Achilles tendon).
Strongest risk factor for acquiring gout is hyperuricemia, which can be caused by:
Underexcretion of uric acid (90% of patients)—largely idiopathic, potentiated by renal failure;
can be exacerbated by certain medications (eg, thiazide diuretics).
Overproduction of uric acid (10% of patients)—Lesch-Nyhan syndrome, PRPP excess, cell
turnover (eg, tumor lysis syndrome), von Gierke disease.
submitted by ∗surgerydoctorca_sgu(6)
This question is testing your knowledge on gout.
In the question stem the examiners are showing you a picture of a hand with extensive tophus formations (often these appear on the external ear, olecranon bursa, or Achilles tendon).
Strongest risk factor for acquiring gout is hyperuricemia, which can be caused by:
Treatment: