FA 2017: Infects B cells through CD21. Atypical lymphocytes on peripheral
blood smear G —not infected B
cells but reactive cytotoxic T cells. ⊕ Monospot test—heterophile
antibodies detected by agglutination
of sheep or horse RBCs.
Use of amoxicillin in mononucleosis
can cause characteristic maculopapular rash.
Patient has infectious mono. Atypical lymphocytes (reactive CD8+ T-cells) are seen on blood smear for infectious mono.