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Retired NBME 20 Answers

nbme20/Block 3/Question#5 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Methotrexate ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—neonem(629)
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Methotrexate would be a drug of choice for psoriasis refractory to topical creams and light therapy; inhibits dihydrofolate reductase in order to decrease skin cell proliferation and reduce inflammatory response.

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69_nbme_420  Cyclosporine can also be used to treat Psoriasis (NOT cyclophosphamide - ans B) +11
len49  Drugs that can be used for psoriasis include cyclosporine, MTX, TNF-alpha inhibitors including Etanercept, lnfliximab, adalimumab, certolizumab, golimumab according to FA +2
medstudent  Kinda summed up in the index - p 791 2nd row halfway down +2
lovebug  as We all know, 1st line therapy of psoriasis is topical corticosteroid, Vit.D analog (Vit.D inhibits keratinocyte proliferation and stimulates keratinocyte differentiation. +1
shakakaka  What page if Fa says that these drugs can be used in psoriasis?) +
srmtn  FA 2019 p 476 +



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