NBME 20 Prostate (NBME Answers)

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Retired NBME 20 Answers

nbme20/Block 3/Question#9 (reveal difficulty score)
A 62-year-old man comes to the physician ...
Prostate 🔍 / 📺 / 🌳 / 📖
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submitted by medschoollovin(14)

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Osteoblastic lesions are associated with prostatic adenocarcinoma mets.

Most other cancer mets to the bone are osteolytic lesions.

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submitted by ∗celeste(96)

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If prostate cancer spreads to other parts of the body, it nearly always goes to the bones first (cancer.org/cancer/prostate-cancer/treating/treating-pain.html)

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submitted by ∗chandlerbas(118)

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Legend:

OB = osteoblastic

OC = osteoclastic/osteolytic

P=prostate, B=breast, K=kidney, T=thyroid, L=lung

my mneumonic: Lead Kettle

P------------B-------------K--------------T------------L

OB-------OB/OC------OC------------OC--------OC/OB

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lilyo @chandlerbas is this pneumonic in order of most common to least common, as in is prostate cancer the most common cause of metastasis to the bone regardless of wether the patient presents with osteoclastic or osteoblastic lesions? +

hello_planet One addition: Breast cancer causes mixed metastases, whereas lung cancer causes either lytic or blastic depending on the cancer type. Small Cell Lung Cancer causes blastic lesions and Non-Small Cell Lung Cancer causes lytic lesions. First Aid 2019: pg. 224 +5

doublethinker Uworld has a great Venn diagram on all the bone mets. +4

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