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NBME 21 Answers

nbme21/Block 1/Question#42 (reveal difficulty score)
A 36-year-old woman undergoes a total ...
Hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ

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submitted by โˆ—welpdedelp(258),
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rcyocCcotlpa stnnegiiim ttha is rentrdsfera grtuhho tisyprarroe etlsoprd


submitted by โˆ—nor16(68),
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pooanoGshdrt rea eht H/LFHS iuorncgpd ariyitptu N o sriea,vo on mose,horn no ecbfkade niohi.itbni

lovebug  THX for great explanation. When I first saw this question, I mistook the gonadotrophs for endometrial cell. so I Choose atrophy. (even that pt undergoes a total hysterectomy) critical mistake... +4  

submitted by โˆ—beeip(138),
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omvd[e ot es]mtncmbuo

submitted by โˆ—paperbackwriter(148),
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ishT can eb eazodaglni to .epausomne cLka of eogesrnt โ€“gt&;โ€“ no taeniveg abedfekc to reirotna yitrtpaui g;โ€“t&โ€“ saidenecr veesll fo FHS nad HL

submitted by halux(14),
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can oesm one alsepe pnaelxi yhw si teh iy?easrpalph

beeip  Loss of negative feedback from resected ovaries leads to gonadotroph hyperplasia. +2  
halux  so, the explanation is that in the absence of Estrogen negative feedback inhibition to LH and FSH, this leads to Gonadotrophs Hyperplasia at the Pituitary resulting in elevated LH and FSH secretion levels? I get busted by this one :/ Thanks in advance! +14  
nala_ula  @halux exactly, there's no negative feedback telling them there is an increase in the hormones (since there are no ovaries) so gonadotrophs work in overdrive to keep stimulating the gonads via FSH and LH. +1  

submitted by โˆ—blue4415(3),
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can odsoarnopGth โ€œlpaiโ€spaeyhr rhaert athn pyhthrerpyo?

kevinsinghkang  wondering the same +  
escherichia95  Hormonal stimulation will lead to production of new cells from stem cells i.e. hyperplasia. Hypertrophy is gene activation, protein synthesis and production of organelles. +  

submitted by halux(14),
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o[edmv to nmt]mbousce

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