Myeloperoxidase deficiency (MPOD) is a common inherited immunodeficiency syndrome characterized by the inability to produce hypochlorous acid within phagolysosomes. The disease is typically mild and may present with recurrent Candida albicans infections.
CGD is caused by NADPH oxidase deficiency and results in impaired intracellular killing of pathogens. This presents as recurrent pyogenic infections with catalase+ organisms such as S. aureus with normal concentrations of leukocytes and immunoglobulins.
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FA2020 9P10 lnyo eeapisdhzm no D"CG tipaten rae ta eiersndac iskr for nteoinicf by leaaa+cst sepeisc blapeac fo nuatlriigzen ihter won 22,OH vaginel gtohecyspa uthwtoi OSR for fihtggin ninic"f.ote Btu lre,nayptpa dicrngaco to shti snei,utqo itsh tesetmnta ldsho erut to elrodaeoeipsMy nyiecedifc sa llew
hyW not iodpeuersx mu?tsidsae sIt teh ptse hritg ni eenwetb DHAPN co(nrcih amgsouonruatl dae)sesi adn OPM
readolpeosixeyM si teh onyl oen auatlcly nlevviod in gmkani eerf ardlac.si taslCeaa meaks 22OH oitn wtr,ae xpidurSeoe idsmtusea esntmeiila ngyoex ,dsaarlic LHD makse lceatat n(o elro ni eacabrlit inll,)ikg dna ON thsnyae,s mkeas ON.
hyw si hetr fexlpriehary and a sbkibain gisn mgaienn atth eetrh si na NMU lieons?
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$279$49omrF athPoma C.h 2 gp. 1:4 MPO fnyeecdici estrsul in fdeivetce vnroisocen fo HO22 ot ClHO. deeIrnacs sikr orf ainddaC sxinnf tuhhgao(l stmo tintasep attmmy.oia)spc botrluNie mreiolttuza tste si amnlor acsbuee eth rostypraeri rsubt is atlyclua isllt a.ntitc siTh pttinea has idncaad nintoefci dan eya,dedl ubt sllit nac llik ashpt a, chwih gesmnliye gose onalg wiht eth ftca hatt hte prieatorrys ubstr is tlils aintt,c tbu itowthu OMP ti mya eb dherined a tlt.lie
$279$49