UWorld Step 1 Qbank: Your world of learning. Subscribe now.

NBME Answers

free120/Block 0/Question#1
A 67-year-old woman with congenital bicuspid ...
Binding to the 30S ribosomal protein🔍

Login to comment/vote.


Aminoglycosides (Which inhibits 30S) are coupled with cell wall active agents - e.g. Penicillins, Vancomycin

(Sketchy Reference on Aminoglycoside Sketch: Beta-lactam bomb!!)




 +0  upvote downvote
submitted by melchior(11),

Couldn't find this in FA or SketchyMicro, but it seems that

"the role of aminoglycosides in the treatment of infective endocarditis is well established. The combination of a beta-lactam with an aminoglycoside shortens the treatment of endocarditis due to... streptococci" 1996 https://www.ncbi.nlm.nih.gov/pubmed/8677414

and "Aminoglycosides are often used in combination with glycopeptides (such as vancomycin) and β-lactams for the treatment of bacterial endocarditis caused by α-haemolytic streptococci, staphylococci and enterococci." 2002 https://academic.oup.com/jac/article/49/3/437/727559




UWorld Step 1 Qbank: Your world of learning. Subscribe now.