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NBME 16 Answers

nbme16/Block 1/Question#14 (14.0 difficulty score)
Lesch-Nyhan syndrome, an X-linked recessive ...
1/50,000🔍
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 +2 
submitted by paloma(9),
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q= ./1000010 qferc(eyun in a 1)=q2m ?e+p=qlps eeury(nqfc fo )yeetoohgsrzu

20200p00q01./05==0,0

tatianalimo  would you write in English? +1  



 +1 
submitted by bingcentipede(129),

FA 2019, p. 57: "The frequency of an X-linked recessive disease in males = q and in females = q^2" Found this on USMLEforum: "X-linked recessive: Prevalence = allele frequency q square = q Carrier state for females = 2q"

Additionally, from Reddit: https://www.reddit.com/r/step1/comments/d492nm/nbme_16_leschnyhan_hardy_weinberg/

If q=1/100,000, p~1. So 2pq~2q=1/50,000. Hard to do with the NBME calculator unfortunately.