bingcentipedeBlack stool because blood in the GI tract?+2
passpleaseI was tempted to pick insulin, because of the orthostatics and sweating that could resemble hypoglycemic episodes. Why are those present in a gastrinoma?+3
deberawr@passplease it's possible that increased gastrin -> peptic ulcers -> perforation -> shock -> sympathetic nervous system overload -> sweating and hypotension+
jsanmiguel415Black stool = melena = bleeding above the ligament of trietz from ulcers+1
rina@passplease according to amboss gastrinomas can cause steatorrhea and malabsorption, in addition to anemia from GI bleeding. that might explain the light headedness and low-ish bp.+
jj375Zollinger Ellison Syndrome --> causes duodenal ulcers that are bleeding causing melena and the low blood volume (symptoms of light headed and low BP). I would guess that sweating is from what @deberawr said of the increased sympathetics from the low blood volume+4
leyblack stools is caused by blood/bleeding in the upper GI like ulcers(stomach,duodenum) and stools with light red blood y caused by lower bleeding like external hemorroids. +
submitted by โzincy7(29)
Immunohistochemical labeling uses antibodies as markers for what they want to find. In this case, we're suspecting gastrin given the symptoms
Note: You should revise the function, stimulation, and site of release for each of the hormones mentioned as well
REFERENCE: Zollinger-Ellison Syndrome