Neural crest cells migrate to form the aorticopulmonary septum and abnormalities associated with neural crest migration in the heart include tetrology of fallot, transposition of the great arteries, and persistent truncus arteriosus. Fusion of the aorticopulmonary septum with the muscular ventricular septum is what forms the membranous septum, so patients with a persistent truncus arteriosus will have VSD as well. (FA2020 p280)
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Neural crest cells migrate to form the aorticopulmonary septum and abnormalities associated with neural crest migration in the heart include tetrology of fallot, transposition of the great arteries, and persistent truncus arteriosus. Fusion of the aorticopulmonary septum with the muscular ventricular septum is what forms the membranous septum, so patients with a persistent truncus arteriosus will have VSD as well. (FA2020 p280)