i_hate_it_here
New stem was describing Bullous pemphigoid, just never heard of BP antigen lol
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taylor5479
Same here. I have literally never heard of "bullous pemphigoid antigen" lol
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chaosawaits
FA2019 page 465: it talks about "bullous pemphigoid antibodies." Antibodies have antigens. Plus, desmoplakin and plakoglobin are components of desmosomes, which is pemphigus vulgaris.
I also almost got torn away by BP antigen though.
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submitted by โbingcentipede(359)
The stem is describing bullous pemphigoid, which produces IgG antibodies hemidesmosomes. (PV is IgG antibodies aginst desmoglein-1 and desmoglein-3, in the oral mucosa).
BP produces the tense blisters that have a negative Nikolsky sign (don't rupture with rubbing). This is because they're supepidermal. Surprised they didn't ask about hemidesmosomes, but I think that that the BP antigen is part of the hemidesmosomes and recruits the autoantibodies.