NBME 20 Answers ↦
FA 2020 Pg 579
Above answer is incorrect because hyperplasia can be either physiological or pathological. Prolonged hyperplasia can set the seed for cancerous growth however.
Stated another way, in pure hypertrophy there are no new cells, just bigger cells containing increased amounts of structural proteins and organelles. Hyperplasia is an adaptive response in cells capable of replication, whereas hypertrophy occurs when cells have a limited capacity to divide. Hypertrophy and hyperplasia also can occur together, and obviously both result in an enlarged (hypertrophic) organ.
FTR Pathoma Ch 1 Dr. Sattar mentions hyperplasia is generally the pathway to cancer, with some exceptions like the prostate and BPH.
Tubular hypertrophy is the natural compensation post renal transplant. Just one of those things you have to know, unfortunately.
Isnt Kidney a labile a tissue & thus should undergo both. This ques is dipshit
Dr Sattar says, kidney is a stable tissue, at least pct is as seen in ATN.
But I read, basically kidneys are mostly formed whatever number of nephrons have to be formed by birth, after that they can only undergo hyperplasia aka increase in size/or regenerate if need be in case of atn. We cant have more number of nephrons.
@brbwhat , do you mean kidneys can only undergo hyperTROPHY?
.... you're not making more cells..... so it cant be hyperplasia